Olprinone Hydrochloride is a highly selective phosphodiesterase 3 (PDE3) inhibitor designed for advanced cardiovascular therapeutic applications. Acting as a potent cardiotonic agent, it provides critical positive inotropic and vasodilating effects, making it an essential tool for increasing cardiac output and enhancing hemodynamic stability in complex clinical settings.
Beyond its primary cardiovascular role, Olprinone Hydrochloride has demonstrated significant efficacy in improving microcirculation and attenuating systemic inflammation. Its specialized application in weaning patients from cardiopulmonary bypass (CPB) and its antioxidative properties against oxidative lung injury highlight its versatility as a high-purity pharmaceutical intermediate for critical care medicine.
Detailed Parameters
| Molecular Formula | C14H10N4O • HCl | Molecular Weight | 286.7 |
|---|---|---|---|
| Purity Level | ≥98% | CAS/Synonyms | Olprinone hydrochloride; Loprinone hydrochloride |
| Certifications | GMP certificate, CFDA | Canonical SMILES | CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2.Cl |
| Storage Condition | -20°C | Stability Period | ≥ 4 years |
| Shipping Method | Room Temperature (US Continental) | Chemical Class | PDE3 Inhibitor / Pharmaceutical Intermediate |
Key Advantages
High Purity Grade
Ensuring ≥98% purity for rigorous pharmaceutical synthesis and clinical research reliability.
Long-term Stability
Exceptional stability profile exceeding 4 years when stored under recommended conditions.
Dual Action Effect
Combines positive inotropic effects with vasodilation to optimize cardiac output efficiency.
Anti-Inflammatory
Proven capability to attenuate inflammation and improve microcirculatory flow.
Regulatory Compliant
Manufactured under strict GMP standards and CFDA certification for global quality assurance.
Specialized Utility
Ideal for CPB weaning protocols and combating meconium-induced oxidative lung injury.
Product Gallery
Management Platforms
Quality Control
Rigorous batch testing using HPLC to ensure purity and structural integrity.
Supply Chain
Optimized logistics ensuring temperature-controlled shipping and rapid delivery.
Regulatory Support
Comprehensive documentation support for CFDA and GMP compliance audits.
Formulation Aid
Expert technical support for customized formulation change requests.
Inventory Tracking
Real-time tracking of API stocks to prevent production downtime.
Safety Management
Strict adherence to MSDS protocols for safe handling of chemical intermediates.
Investment Return Comparison
| Performance Metric | Standard API Grade | Our Premium Olprinone |
|---|---|---|
| Purity Level | ≥95% | ≥98% (High Precision) |
| Shelf Life | 2-3 Years | ≥ 4 Years |
| Regulatory Approval | Basic Grade | GMP & CFDA Certified |
| Delivery Speed | Standard Lead Time | Expedited Global Shipping |
| Technical Support | Limited | Full Formulation Assistance |
Frequently Asked Questions
Olprinone Hydrochloride acts as a selective phosphodiesterase 3 (PDE3) inhibitor, which increases cardiac contractility (positive inotropic effect) and promotes vasodilation.
To ensure a stability period of 4 years or more, it must be stored at -20°C in a dry, protected environment.
Yes, we accept formulation change requests to meet specific pharmaceutical requirements for different drug delivery systems.
Our products are supplied with comprehensive GMP certificates and CFDA documentation to ensure international quality standards.
Yes, Olprinone has shown potent antioxidative and anti-inflammatory effects, particularly in studies involving meconium-induced oxidative lung injury.
While stored at -20°C, it is shipped at room temperature within the continental US; however, shipping protocols may vary for other regions to ensure stability.
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