Urapidil Hydrochloride is a high-potency pharmaceutical intermediate characterized as an orally active α1-adrenoceptor antagonist and 5-HT1A receptor agonist. Specifically engineered for therapeutic efficacy, it exhibits a pIC50 of 6.13 against α1-adrenoceptors and 4.38 against α2-adrenoceptors, making it a critical component in the development of antihypertensive medications.
Supplied by Kunxiangda, a recognized leader in the pharmaceutical manufacturing sector, this product is synthesized under strict adherence to Good Manufacturing Practices (GMP). With certification from the CFDA (China Food and Drug Administration), Kunxiangda ensures that every batch of Urapidil Hydrochloride meets the most rigorous global standards for purity, safety, and pharmacological stability.
Detailed Parameters
| CAS Number | 64887-14-5 | Molecular Formula | C20H30ClN5O3 |
|---|---|---|---|
| Molecular Weight | 423.94 | EINECS No. | 636-348-0 |
| Appearance | Solid | Storage Temperature | 4°C |
| Storage Condition | Sealed, away from moisture | Pharmacological Action | Antihypertensive |
| Receptor Activity | α1-antagonist / 5-HT1A agonist | Certification | GMP / CFDA Certified |
Key Advantages
GMP Certified Quality
Produced in CFDA-approved facilities ensuring strict adherence to Good Manufacturing Practices for maximum safety.
High Purity Standards
Rigorous analytical testing ensures the chemical integrity and precise pIC50 values for pharmaceutical stability.
Targeted Bioactivity
Optimized dual action on α1-adrenoceptors and 5-HT1A receptors for superior antihypertensive performance.
Consistent Batch Supply
Scalable manufacturing capabilities allow for stable, long-term supply of high-grade pharmaceutical intermediates.
Strict Quality Control
Comprehensive internal audits and quality checks to prevent contamination and ensure potency.
Regulatory Compliance
Full documentation support provided to meet international regulatory requirements for API sourcing.
Product Gallery
Management Platforms
Inventory Tracking
Real-time monitoring of raw materials and finished pharmaceutical intermediates.
Process Optimization
Advanced synthesis controls to ensure consistent molecular weight and purity.
Compliance Alerts
Automated systems to ensure all batches align with CFDA and GMP regulations.
Cold Chain Logic
Strict 4°C temperature management system for sensitive chemical storage.
Packaging Security
Hermetic sealing protocols to protect products from moisture and degradation.
Quality Assurance
Multi-stage verification process from raw material input to final product delivery.
Investment Return Comparison
| Evaluation Metric | Standard Grade | Kunxiangda Premium |
|---|---|---|
| Purity Level | 98% - 99% | >99.5% Pharma Grade |
| Regulatory Support | Basic COA | Full GMP/CFDA Dossier |
| Stability Period | Short-term | Extended Cold-Chain Stability |
| Batch Consistency | Variable | High Precision (pIC50 Validated) |
| Risk Mitigation | Moderate | Low (Certified Quality Control) |
Frequently Asked Questions
It is primarily used as an active pharmaceutical ingredient (API) or intermediate for creating antihypertensive drugs due to its dual action as an α1-adrenoceptor antagonist and 5-HT1A receptor agonist.
GMP (Good Manufacturing Practices) ensures that products are consistently produced and controlled according to quality standards, minimizing risks such as cross-contamination and ensuring batch-to-batch uniformity.
To maintain its chemical stability and potency, it should be stored at 4°C in a sealed container, kept away from moisture and direct light.
Yes, as a CFDA-certified supplier, we provide comprehensive technical data sheets, Certificates of Analysis (COA), and GMP documentation to facilitate global trade.
The pIC50 value indicates the potency of the inhibitor. A value of 6.13 against α1-adrenoceptors confirms the high affinity and effectiveness of the molecule in blocking these receptors.
Unlike general chemicals, pharmaceutical intermediates like Urapidil Hydrochloride are produced under strict medical-grade purity standards and regulated by health authorities to ensure biological safety.
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