Sevoflurane, as a new active drug of inhalation anesthesia, occupies an important position in the field of modern anesthesia with its excellent anesthetic effect, low side effects and safety. It not only provides a more stable and controllable anesthesia scheme for anesthesiologists, but also provides a milder and faster anesthesia experience for patients. With the development of anesthesiology and pharmacology, the clinical application of sevoflurane will be more extensive, and its future influence in the field of anesthesia will be further expanded.
Clinical Application of Sevoflurane
- Adult anesthesia
Sevoflurane is widely used in adult surgery, especially in patients with low tolerance to narcotic drugs, and its advantages are more obvious. Sevoflurane not only plays an important role in routine surgery, but also can ensure accurate control of anesthesia depth in many high-risk operations. For example, sevoflurane can effectively maintain the patient's anesthesia and ensure the smooth operation during complicated surgical procedures such as heart surgery, brain surgery and liver transplantation.
The mild onset and rapid recovery characteristics of sevoflurane greatly shorten the postoperative recovery time. Patients wake up quickly after operation, and there are fewer adverse reactions such as nausea and vomiting, and the recovery process after operation is smoother, and the comfort of patients has also been significantly improved.
- Children's anesthesia
For children patients, the choice of anesthetic drugs is particularly important. The application of sevoflurane in pediatric anesthesia has been widely recognized. Because of its low irritation and good anesthesia depth control, sevoflurane is especially suitable for children's surgery. Compared with traditional anesthetics, sevoflurane has a more stable anesthetic effect, and the recovery process of children patients is relatively fast, with less postoperative adverse reactions.
It is worth noting that the dosage of anesthetic drugs used in children is usually complicated, and anesthesiologists need to adjust the concentration of sevoflurane according to the weight, age and individual differences of children. This puts forward higher requirements for the technical level of anesthesiologists.
- Anesthesia in elderly patients
Sevoflurane is also suitable for anesthesia of elderly patients. Elderly patients usually have a variety of basic diseases (such as heart disease, hypertension, etc.), so the use of narcotic drugs needs to be more cautious. Compared with other narcotic drugs, sevoflurane has less inhibition on cardiovascular system and will not lead to excessive blood pressure drop or heart rate slowdown. Therefore, it has become the first choice of anesthetic drugs for elderly patients in surgery.
- Day surgery
Daytime surgery refers to the way that patients can go home the same day without hospitalization after surgery. Sevoflurane is an ideal choice for daytime surgery because of its rapid induction and waking time. Patients can quickly regain consciousness after operation, which reduces the retention time of anesthetic drugs and helps to reduce the burden of anesthesia on patients.
Advantages and Safety of Sevoflurane
Sevoflurane, as a active pharmaceutical ingredient, has many outstanding advantages in clinic:
- Lower side effects
Sevoflurane has relatively few side effects, especially in the case of long-term use, it will not cause serious liver and kidney damage or nausea and vomiting. In addition, sevoflurane does not have a significant cardiovascular inhibitory effect like some anesthetic drugs, and patients can spend it smoothly during and after anesthesia.
- Good control
The anesthesia depth of sevoflurane is positively correlated with its concentration. Anesthesiologists can flexibly adjust the concentration of sevoflurane according to the specific situation of patients to achieve accurate control of anesthesia depth. This makes sevoflurane have a strong advantage in complex surgery and can ensure the smooth operation.
- Shorter recovery time
Sevoflurane has the characteristics of rapid onset and recovery, and patients can quickly regain consciousness after surgery. This feature is especially suitable for operations that require short recovery time, such as daytime surgery and minimally invasive surgery.