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For those suffering from chronic conditions, metformin is a regular active ingredient in diabetes management. As the first-line treatment for type 2 diabetes, it helps to lower blood sugar levels by improving the sensitivity of body tissues to insulin and decreasing glucose production in the liver. Metformin is often combined with lifestyle modifications to achieve better glucose control without causing weight gain, a common problem with other diabetes medications.


Healthcare facilities often negotiate prices based on volume purchasing agreements. Larger hospitals may receive discounts that significantly lower their costs, while smaller clinics may not have the same bargaining power. Additionally, fluctuations in the pharmaceutical market can affect prices, with periods of shortage or increased demand leading to temporary spikes in cost.


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Once a viable API is developed, extensive clinical trials are conducted to evaluate its safety and efficacy in humans. Regulatory bodies, such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), require comprehensive data on the API before granting approval for the drug's market release. These regulatory frameworks ensure that only safe and effective medicines reach patients.


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