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Sevoflurane’s mechanism of action isn’t limited to GABA and excitatory signals. It also affects other neurotransmitter systems, including the glutamate system. Glutamate is an excitatory neurotransmitter, and sevoflurane can reduce its release and effects, further contributing to the overall CNS depression observed during anesthesia.

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The low blood-gas solubility of sevoflurane allows for a faster equilibrium between the alveoli and the bloodstream. This results in a quick induction of anesthesia and a prompt recovery after discontinuation. The low solubility also contributes to the precise control of anesthetic depth during procedures.

Pyrroloquinoline quinone (PQQ) is another significant nutrient that is gaining attention for its health-promoting properties. It is recognized as a potent antioxidant that supports mitochondrial health. Mitochondria are the powerhouses of the cell, and maintaining their function is crucial for overall cellular energy production. PQQ has been shown to promote the growth of new mitochondria, a process known as mitochondrial biogenesis, which can lead to increased energy production and improved cellular health.


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