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The primary function of SDS in gel electrophoresis is to denature proteins. Denaturation refers to the process by which proteins lose their native structure due to the disruption of non-covalent interactions, such as hydrogen bonds and hydrophobic interactions. When a protein is treated with SDS, it unfolds into a linear form, and the bound SDS molecules coat the protein, ensuring that the negative charge is evenly distributed.


Active Pharmaceutical Ingredients (APIs) play a critical role in the pharmaceutical industry, serving as the essential components that produce the therapeutic benefits of a drug. From the initial stages of drug development to mass production, APIs are the backbone of pharmaceutical manufacturing, influencing both the efficacy and safety of the medications we consume.


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After a drug is approved, post-market surveillance is essential to monitor its long-term effects in the general population. The API’s role continues, as real-world data can provide insights into its performance, guiding dosage adjustments and informing healthcare providers about potential safety concerns.


Physical Performance and Recovery


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