Following the identification of a suitable API, the next step is the formulation development. This process involves combining the API with excipients to create a dosage form, such as tablets, capsules, or injectables. The formulation must ensure that the API is delivered effectively, maintaining its stability, solubility, and bioavailability. Pharmaceutical scientists work meticulously to optimize formulations that maximize therapeutic outcomes while minimizing side effects.
In the vast landscape of modern medicine, active pharmaceutical ingredients (APIs) play a crucial role. These compounds are the primary ingredients responsible for the therapeutic effects of medications. The term API refers to any substance or mixture of substances intended to be used in the manufacture of a pharmaceutical product and is responsible for its pharmacological activity. A comprehensive understanding of pharmaceutical APIs is essential for healthcare professionals, regulatory bodies, and pharmaceutical companies alike.
1. Coagulants (e.g., Alum) Coagulants are added to water to destabilize particles, allowing them to clump together into larger aggregates or flocs. This process is crucial for removing suspended solids and impurities.