Despite their importance, the production of pharmaceutical intermediates is not without challenges. The increasing complexity of drug formulations necessitates a greater diversity of intermediates, which can strain existing manufacturing processes. Additionally, regulatory demands are ever-tightening, necessitating adherence to good manufacturing practices (GMP) and environmental considerations.
Regional and global factors, plus preparations and delayed cold weather, helped ISO New England survive the winter of 2014-15 with fewer operational issues and less extreme prices, the ISO said Friday.