Ammonia is a toxic byproduct of protein metabolism. In healthy individuals, the liver efficiently eliminates ammonia by converting it into urea through the urea cycle. However, in liver dysfunction or cirrhosis, this detoxification process is impaired, leading to the accumulation of ammonia in the bloodstream. This condition, known as hyperammonemia, can result in serious neurological complications, collectively referred to as hepatic encephalopathy. Symptoms may range from mild confusion to severe cognitive decline, indicating the brain's sensitivity to elevated ammonia levels.
PQQ is a small nutrient that is naturally present in certain foods like fermented soybeans, spinach, and green tea. However, it is relatively difficult to consume adequate amounts through diet alone, making supplementation a practical choice for many individuals. The unique structure of PQQ enables it to serve multiple roles in the body, functioning as an antioxidant and playing a crucial role in cellular energy metabolism.
Moreover, APIs can be derived from various sources they may be synthesized chemically, extracted from natural sources, or produced through biotechnological processes. For example, many antibiotics are derived from molds or bacteria, while other APIs may be manufactured using recombinant DNA technology. This diversity in sources reflects the wide-ranging therapeutic profiles of the APIs, accommodating a broad spectrum of diseases and health conditions.