stability testing of active pharmaceutical ingredients and finished pharmaceutical products

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Understanding API Manufacturing


Ticagrelor, renowned for its ability to inhibit platelet aggregation, stands as a crucial medication in the prevention of life-threatening cardiovascular events such as heart attacks and strokes. With its multifaceted benefits, ticagrelor offers significant advantages to individuals with a history of cardiovascular issues or those undergoing certain heart surgeries. Let’s explore the manifold benefits of ticagrelor and its role in promoting cardiovascular health.

Disinfection is a critical stage in the water treatment process, aimed at eliminating pathogens that can cause waterborne diseases. Chlorine is perhaps the most widely used disinfectant, added to the water in precise doses to ensure sufficient microbial kill while minimizing harmful by-products. Alternative disinfectants are also employed, such as ozone and ultraviolet (UV) light. Each method requires careful dosing to achieve effective disinfection without compromising water quality.


Sodium thiocyanate (NaSCN) is a white, crystalline compound that plays a significant role in various industrial applications due to its unique chemical properties. It is the sodium salt of thiocyanic acid and can be produced through the reaction of sodium hydroxide with thiocyanate. Known for its solubility in water and other solvents, sodium thiocyanate has gained prominence in numerous fields such as chemistry, agriculture, and the pharmaceutical industry.


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4. Formulation Finally, APIs are formulated into final dosage forms—tablets, capsules, injectables, etc.—involving the addition of excipients that facilitate stable and effective delivery of the drug.


3. Scale Inhibitors Hard water can lead to scaling within the cooling tower, necessitating the use of scale inhibitors. These chemicals work by interfering with the formation of mineral deposits, thus keeping the heat exchange surfaces clear and ensuring efficient heat transfer.


Challenges in API and Formulation Development


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