The primary objective of chemical treatment in cooling towers is to maintain water quality, thereby ensuring optimal heat exchange. Poor water quality can lead to several issues, such as scale formation, corrosion of metal components, and biological fouling, all of which diminish system efficiency and might lead to costly downtime. Scaling occurs when dissolved minerals precipitate and accumulate on heat exchange surfaces, restricting flow and insulating heat exchange, which can result in increased energy costs. Corrosion, on the other hand, compromises the structural integrity of cooling tower components, leading to leaks and potential operational failures.
In the pharmaceutical industry, the term Active Principle Ingredient (API) holds significant importance as it pertains to the core component of a drug that provides therapeutic effects. Understanding the characteristics, development, and regulatory challenges surrounding APIs is crucial for stakeholders in the healthcare sector, including pharmaceutical manufacturers, healthcare professionals, and patients.
3. Atorvastatin This API is utilized for lowering cholesterol and preventing cardiovascular diseases. Acting as a statin, atorvastatin inhibits the enzyme HMG-CoA reductase, which plays a central role in cholesterol production in the liver.
After successful preclinical trials, the API enters clinical development, where it is tested in a series of progressively larger phases in human subjects. Each phase is designed to gather more data about the drug's safety and effectiveness. Depending on the results of these studies, the drug may eventually receive approval from regulatory bodies such as the U.S. Food and Drug Administration (FDA) or the European Medicines Agency (EMA), paving the way for commercial production.
api drug substance