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The mechanism by which NMU induces mutations is primarily through its alkylating properties. Upon exposure, NMU can add alkyl groups to DNA bases, leading to mispairing during DNA replication. This results in transitions or transversions in the nucleotide sequence, which can ultimately lead to permanent mutations. If these mutations occur in critical genes responsible for regulating cell growth and division, such as proto-oncogenes and tumor suppressor genes, they may lead to uncontrolled cell proliferation and cancer.


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5. Biomedical Applications In the field of biomedicine, polyacrylamide is used in drug delivery systems and as a component in hydrogels for tissue engineering. Its biocompatibility makes it suitable for these applications, although further research is being conducted to enhance its properties.


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In the pharmaceutical industry, N,N-dimethylurea plays a pivotal role as a building block in the synthesis of various bioactive compounds. Its ability to participate in chemical reactions, such as condensation and nucleophilic substitution, makes it a versatile intermediate in drug development. Researchers investigate its potential as a scaffold for designing new pharmaceuticals with specific biological activities. Furthermore, some studies point to its possible applications in the treatment of diseases, such as cancer, where nitrogen-containing compounds have shown promise in targeted therapies.


 

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