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This is crucial because, without SDS, proteins of different sizes and shapes would migrate through the gel based on both size and net charge. The presence of SDS levels the playing field, allowing proteins to be separated solely by their molecular weight. Therefore, during electrophoresis, all proteins will experience the same electric field-driven force, enabling their separation based on size alone.
Active Pharmaceutical Ingredients are the substances in a drug that produce the intended effects. They are distinct from excipients, which are inactive substances used to facilitate the delivery of the API. Regardless of the form a medication takes—be it a pill, liquid, or injectable—the quality and purity of the API are fundamental to the drug's effectiveness and safety.
As with any medication, pentoxifylline may have side effects. Common side effects include gastrointestinal issues such as nausea, vomiting, and diarrhea. Additionally, patients may experience dizziness, headache, or palpitations. Severe allergic reactions, although rare, can occur and require immediate medical attention.