Vitamin B12 and folic acid differ in their chemical structures. Vitamin B12, also known as cobalamin, is a complex molecule that contains cobalt. In contrast, folic acid, also referred to as vitamin B9 or folate, is a simpler molecule. Understanding their distinct structures is fundamental to appreciating their unique roles in the body.
Stability studies typically involve long-term, accelerated, and intermediate testing. Long-term studies provide information about the API’s stability under normal storage conditions, often conducted over a period of 12 months or more. Accelerated testing involves higher temperatures and humidity levels to expedite decomposition, allowing manufacturers to predict long-term stability in a shorter time frame. Intermediate testing often serves as a bridge, assessing stability under conditions that fall between long-term and accelerated studies.
Stabilizers are crucial for protecting plastics from degradation caused by exposure to heat, light, and oxygen. Without stabilizers, plastics can become brittle or discolored, resulting in diminished mechanical performance and shorter service life. UV stabilizers, for example, are essential for outdoor applications where exposure to sunlight can be detrimental. Metal stearates and chlorinated paraffins are often added to stave off thermal degradation during manufacturing processes, ensuring that the plastic maintains its integrity during production and usage.