Coagulants are chemicals that help in the removal of suspended solids. They work by neutralizing the negative charges on particles suspended in water, causing them to clump together. This process, known as coagulation, is crucial in municipal water treatment plants where reducing turbidity is vital. Common coagulants include aluminum sulfate (alum) and ferric chloride. These materials not only assist in particle removal but also help in the subsequent process of sedimentation, where larger clumps of particles settle at the bottom for easy removal.
Once APIs are formulated into FPPs, stability testing becomes even more critical. FPPs might contain various excipients that can interact with the active ingredient, influence its stability, and affect the overall product performance. For example, the choice of excipients, packaging materials, and the manufacturing process can all impact the shelf life of a medication.
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