Intermediates can also play a significant role in drug development by serving as platforms for the modification and optimization of lead compounds. For instance, in the process of drug discovery, researchers often start with a lead compound known to interact with a specific biological target. Through a series of modifications, including the alteration of intermediates, scientists can enhance the potency, selectivity, and reduce toxicity of the lead compound, ultimately improving its therapeutic profile. This iterative approach can lead to the identification of novel drugs with improved efficacy and safety profiles.
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The journey of an API begins in the laboratory, where chemists and biologists work to identify and develop compounds that can potentially treat diseases. This process often involves extensive research, testing, and optimization of the molecular structure to enhance efficacy and safety. The goal is to identify a molecule that can effectively interact with biological systems to modulate a specific pathological process.