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2. Non-Reinforcing Fillers Unlike reinforcing fillers, non-reinforcing fillers typically serve to reduce costs and improve processing ease rather than enhance mechanical strength. Examples include calcium carbonate, talc, and clay. These fillers can also enhance certain properties, such as thermal conductivity or opacity, depending on the specific application.


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Intermittent claudication (IC) is a common manifestation of peripheral artery disease (PAD) characterized by pain or cramping in the legs during physical activity, particularly walking. This pain occurs due to insufficient blood flow to the muscles, often caused by atherosclerosis, where arteries become narrowed by fatty deposits. While lifestyle modifications and surgical options play vital roles in managing IC, pharmacological interventions, including pentoxifylline, have emerged as potential treatments.


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