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Moreover, the relationship between pharmaceutical companies and intermediates manufacturers is often collaborative. These manufacturers work closely with their clients during the drug development process to provide not only the intermediates but also insights into chemical synthesis and process optimization. This collaboration can significantly shorten the time-to-market for new drugs and can also lead to cost savings in the overall manufacturing process. As regulatory hurdles increase, the ability of intermediates manufacturers to navigate complex compliance requirements also becomes a valuable asset for pharmaceutical companies.
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On the other hand, excipients are the non-active components of a drug formulation that serve as vehicles for the API. They may enhance the stability of the medication, aid in the manufacturing process, improve taste, or assist in the drug's absorption in the body. Common excipients include fillers, binders, preservatives, and flavoring agents. For instance, lactose is often used as a filler in tablets, while magnesium stearate serves as a lubricant during production. Although they do not provide therapeutic effects, excipients can influence the bioavailability and efficacy of the active ingredients, making their selection critical in drug formulation.
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