Bulk drug intermediates are chemical compounds that are produced during the synthesis of APIs. These substances are not finished drugs themselves but serve as essential building blocks, helping in the transition from raw materials to final pharmaceuticals. They undergo further processing and refinement to create the final active ingredients that are used in medicines.
The role of APIs is not limited to conventional medications; they are also crucial in the development of biologics and biosimilars, which are created from living organisms. Biologics often consist of large, complex molecules such as proteins, which require specialized processes for their production and quality control. Therefore, understanding the characteristics and behaviors of APIs is fundamental for pharmacists, researchers, and manufacturers alike.
api in pharmacy definition
Beyond energy production, mitochondria are involved in several other critical cellular functions. They are key players in the regulation of metabolic pathways, the maintenance of cellular calcium homeostasis, and the initiation of programmed cell death or apoptosis. Their ability to regulate the balance between energy production and reactive oxygen species (ROS) generation is vital for cellular health. Excessive ROS can lead to oxidative stress, which has been implicated in various diseases, including cancer, neurodegenerative disorders, and aging.