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Active Pharmaceutical Ingredients (APIs) are the essences of drugs, responsible for their therapeutic effects. However, the journey from concept to market-ready pharmaceuticals is complex and often relies heavily on intermediates—substances produced during the synthesis of an API. These API intermediates serve multiple purposes in drug development and manufacturing, offering a crucial bridge in the creation process.


Penicillin, a pioneer among antibiotics, once had a production process that caused significant environmental pollution. In recent years, with the application of eco-friendly pharma intermediates, penicillin production has become cleaner and more efficient. For instance, using biocatalysis instead of chemical catalysis not only increases penicillin yield but also significantly reduces wastewater and gas emissions, achieving green production processes. Additionally, optimizing fermentation techniques has improved the biosynthesis efficiency of penicillin, reduced chemical synthesis steps, and lowered energy and resource consumption.

2. Secondary Anti-Static Additives These additives work differently; rather than providing immediate anti-static properties, they modify the material's properties over time. Secondary additives often include carbon black, metal powders, or other conductive fillers that create a conductive network within the plastic matrix. This allows static electricity to dissipate more effectively over the lifespan of the product.


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Aspirin is another important NSAID with additional properties, including antiplatelet effects. It is often used in low doses to reduce the risk of heart attacks and strokes by preventing blood clots. In higher doses, aspirin can treat pain and inflammation in conditions like arthritis. However, its use is limited in children due to the risk of Reye’s syndrome, a serious illness that affects the liver and brain.


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