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The mechanism by which NMU induces mutations is primarily through its alkylating properties. Upon exposure, NMU can add alkyl groups to DNA bases, leading to mispairing during DNA replication. This results in transitions or transversions in the nucleotide sequence, which can ultimately lead to permanent mutations. If these mutations occur in critical genes responsible for regulating cell growth and division, such as proto-oncogenes and tumor suppressor genes, they may lead to uncontrolled cell proliferation and cancer.
nitroso methyl urea...
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Ticagrelor plays a crucial role in ensuring smooth blood flow, particularly in patients at high risk of developing fatal blood clots. By inhibiting platelet aggregation, ticagrelor helps to prevent the formation of obstructions within the blood vessels, which can impede circulation and lead to serious complications. This benefit is especially significant for individuals with underlying cardiovascular conditions or risk factors predisposing them to thrombotic events, where maintaining optimal blood flow is paramount for overall health and well-being.
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