Regulatory agencies, such as the Food and Drug Administration (FDA) and the European Medicines Agency (EMA), require comprehensive stability data as part of the submission process for new drug applications. These entities have established specific guidelines that pharmaceutical companies must follow to ensure that their products meet safety and efficacy standards.
PQQ is a quinone compound that was first discovered in the early 1970s. It is found in a variety of foods, particularly in fermented products, and is known to play a critical role as a cofactor in enzymatic reactions. PQQ supports the function of certain dehydrogenases and is involved in cellular respiration, aiding the conversion of glucose and other substrates into energy. One of the key aspects of PQQ is its ability to stimulate mitochondrial biogenesis, a process that enhances the number and function of mitochondria within cells.
In addition to organic pollutants, sewage water often contains heavy metals such as lead, mercury, cadmium, and arsenic. These metals can originate from industrial discharges, leaching from rusting pipes, or runoff from urban areas. Heavy metals are particularly concerning because they are non-biodegradable and can accumulate in the environment, leading to serious health risks for both humans and wildlife. Chronic exposure to even low concentrations of heavy metals can result in a range of health issues, including neurological disorders, cancer, and reproductive problems.
While PQQ has garnered significant attention for its health benefits, it is essential to approach supplementation with knowledge and caution. Individuals should consult with healthcare professionals before starting any new supplement regimen, particularly those with underlying health conditions or those who are pregnant or nursing.