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In addition to regulatory aspects, the API list serves as a valuable resource for researchers and developers in the pharmaceutical field. It acts as a starting point for exploring new therapeutic options and understanding the mechanisms of action behind various drugs. Researchers can identify gaps in existing treatments and develop new APIs to address unmet medical needs, thus driving innovation and improving patient care.


PQQ is a redox cofactor that was first identified as a required nutrient in bacteria. While its role in human health is still being explored, research suggests that PQQ is involved in numerous biological processes. It is known to promote the growth of new mitochondria—a process known as mitochondrial biogenesis. This is particularly important as mitochondrial function declines with age, leading to reduced energy levels and increased oxidative stress.


One of the primary challenges in reverse osmosis processes is the formation of scale on the membranes. Scaling occurs due to the precipitation of dissolved salts and minerals, which can significantly reduce the efficiency of the system and lead to costly downtime. Antiscalants are chemical agents specifically designed to prevent scale formation by inhibiting the crystallization of salts. These chemicals work by dispersing the minerals in solution, thereby preventing them from adhering to the membrane surface. Common antiscalants include phosphonates and polyacrylic acids.


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While active ingredients are critical for a drug's efficacy, inactive ingredients—also known as excipients—play an equally important role. These substances do not have a therapeutic effect but are essential for the formulation, stability, and delivery of the active ingredient. Inactive ingredients can include binders, fillers, preservatives, colorants, and flavoring agents.


The pharmaceutical intermediate market is subject to stringent regulatory oversight. Regulatory agencies, such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), impose strict guidelines to ensure the safety and efficacy of pharmaceutical products. Manufacturers must adhere to Good Manufacturing Practices (GMP) and other regulations to ensure that intermediates meet quality standards.


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