The API supply chain is global, with suppliers often located in various countries. Regions such as Asia, particularly India and China, have emerged as leading producers of APIs, primarily due to their cost-effective manufacturing capabilities and established regulatory frameworks. However, this global setup also poses risks, including geopolitical tensions, regulatory changes, and supply disruptions caused by natural disasters or pandemics, as observed during the COVID-19 crisis.
The process of developing and manufacturing APIs is fraught with challenges. One significant hurdle is the regulatory landscape, which mandates compliance with Good Manufacturing Practices (GMP) and other quality assurance protocols. Pharmaceutical companies must invest heavily in maintaining compliance, which can be both time-consuming and costly.
Incorporating PQQ into one’s diet can be achieved through natural food sources or supplements. While foods rich in PQQ can offer substantial health benefits, supplementation may provide a more concentrated dose, particularly for individuals looking to enhance their mitochondrial function for specific health needs. However, as with any supplement, it is essential to consult healthcare professionals prior to starting a regimen.