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Additionally, LOLA has been explored in the context of sports nutrition, as it may aid in reducing muscle fatigue and enhancing recovery through its role in nitrogen metabolism. This application is particularly relevant for athletes experiencing high levels of physical stress, where optimal recovery is crucial for performance.


The COVID-19 pandemic has also accelerated change within the active pharma sector. The urgent need for vaccines and treatments underscored the importance of a robust supply chain and the ability to rapidly scale production. Pharmaceutical companies adapted quickly, showcasing their capacity for innovation and collaboration. This rapid response not only highlighted the potential of active pharma but also set new benchmarks for speed and efficiency in drug development.


PQQ is a redox cofactor that is naturally found in various foods, such as kiwifruit, fermented soybeans, green peppers, and spinach. It has been researched for its potential to improve mitochondrial function, which is vital for energy production in our cells. Mitochondria are often referred to as the powerhouses of the cell, converting nutrients into energy. With age, mitochondrial function can decline, leading to fatigue and various health issues. This is where PQQ comes into play.


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While cooking can alter the nutrient content of foods, steaming or microwaving vegetables helps preserve their Vitamin C content better than boiling.

1. Synthesis This step involves chemical reactions to create the API from raw materials. The methods of synthesis can vary widely, utilizing techniques such as organic chemistry, biotechnology, or even green chemistry to minimize environmental impact.


In the era of smart manufacturing, the development of pharma intermediates is also experiencing new opportunities. Utilizing advanced technologies like big data, artificial intelligence, and continuous flow chemistry, pharmaceutical companies can precisely control synthesis reactions, achieving efficient production of intermediates and customized batches of antibiotics. For example, real-time monitoring of reaction conditions and automatic parameter adjustments can significantly increase the yield and purity of intermediates, reduce by-product formation, and optimize antibiotic production processes.

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