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For APIs, stability testing serves to assess how the chemical, physical, and biological characteristics of the ingredient change over time. Various factors can influence API stability, including temperature, moisture, light exposure, and the presence of catalytic substances. Testing is generally conducted according to guidelines established by regulatory bodies such as the International Council for Harmonisation (ICH).


The Dynamic Duo for Health CoQ10 and PQQ


In recent years, there has also been a growing interest in the development of greener and more sustainable methods for API production. This includes utilizing environmentally friendly solvents, reducing waste, and employing energy-efficient processes. The pharmaceutical industry is under pressure to adopt sustainable practices, not only to protect the environment but also to improve public perception and meet regulatory requirements.


India, in particular, is known as the pharmacy of the world. Indian API manufacturers export significant quantities of APIs to many countries, including the United States and Europe. The country has established itself as a leader in the production of generic drugs and APIs, thanks to its advanced technologies and stringent quality control measures. However, it faces challenges, including regulatory scrutiny and the need to meet global quality standards.


On the other hand, biologics are large, complex molecules derived from living organisms, including proteins, nucleic acids, and cells. Biologics often include monoclonal antibodies, vaccines, and gene therapies. The mode of action for biologics can be quite different from that of small molecules; they may target specific pathways in immune response or cellular activity. The development and production of biologics require advanced biotechnology tools and techniques, making them significantly more complex and costly. However, they often offer innovative treatments for diseases that were previously untreatable or difficult to manage.


types of active pharmaceutical ingredients

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Another interesting effect of theobromine is its potential to act as a cough suppressant. Studies have shown that theobromine may be more effective than codeine in suppressing coughs. This property arises from its ability to relax the smooth muscles of the bronchial tissues, making it a potential candidate for the treatment of respiratory conditions such as asthma. However, larger studies are needed to fully understand its efficacy and safety in this area.


Sodium cumene sulfonate is derived from the sulfonation of cumene, an aromatic hydrocarbon that serves as a precursor. The structure of sodium cumene sulfonate features a sulfonate group (-SO3Na), which imparts its surfactant qualities. This compound is typically available as a pale yellow to brown liquid and is soluble in water, providing ease of use in various formulations.


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