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3. Fillers Fillers are used to improve the mechanical properties of plastics while also reducing production costs. Common fillers include calcium carbonate, talc, and clays. These additives can enhance strength, rigidity, and thermal stability, making the plastic more suitable for various applications. Fillers also reduce the amount of expensive resin needed in formulation, making plastics more cost-effective.
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Once a drug candidate is deemed successful, the focus shifts to the production of the API. This typically involves scaling up the synthesis process from laboratory to industrial production while maintaining strict adherence to Good Manufacturing Practices (GMP). The production process can vary significantly depending on the API's complexity, with some requiring multi-step synthesis, while others can be extracted directly from natural sources.
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