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In recent years, there has been a noticeable shift towards biologics, which comprise APIs sourced from living organisms. This trend is driven by the increasing prevalence of chronic diseases and the demand for more targeted therapies. Biologics offer unique mechanisms of action and often come with a lower risk of side effects compared to traditional small-molecule drugs.


Protease, also known as peptidase or proteinase, is the enzyme that facilitates the digestion of proteins. Like amylase, protease is secreted by the pancreas into the small intestine. It is activated from an inactive form known as trypsinogen, which is converted into trypsin in the presence of another enzyme, enterokinase. Protease works by cleaving the peptide bonds between amino acids in proteins, breaking them down into smaller peptides and eventually into individual amino acids.


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Dry polyacrylamide is characterized by its high molecular weight, which can range from several thousand to several million g/mol. This large molecular structure contributes to its functionality as a flocculant, thickener, and stabilizer. When mixed with water, dry polyacrylamide forms a gel-like substance that exhibits remarkable viscosity and can retain significant amounts of water. This property makes it ideal for applications where water retention is necessary.


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Understanding API in Pharmacy Definitions and Significance


 

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