PQQ is a naturally occurring compound that was first identified in bacteria in the 1970s. Since then, research has revealed that it is not only present in various foods but also produced endogenously in smaller amounts within the human body. Notably, PQQ is known for its role as an antioxidant, helping to combat oxidative stress that can lead to cellular damage and various chronic diseases.
In addition to enhancing GABA activity, sevoflurane also blocks the transmission of excitatory signals. Excitatory signals are responsible for stimulating nerve cells and promoting wakefulness. By interfering with these signals, sevoflurane further contributes to the induction of anesthesia.