active pharmaceutical ingredient definition

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While active ingredients are critical for a drug's efficacy, inactive ingredients—also known as excipients—play an equally important role. These substances do not have a therapeutic effect but are essential for the formulation, stability, and delivery of the active ingredient. Inactive ingredients can include binders, fillers, preservatives, colorants, and flavoring agents.


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Moreover, PQQ has been shown to promote mitochondrial biogenesis, the process by which new mitochondria are formed within cells. Mitochondria are often referred to as the “powerhouses” of the cell, producing adenosine triphosphate (ATP), the energy currency of life. By enhancing mitochondrial function, PQQ can improve cellular energy levels, leading to better overall health and vitality.


Active ingredients are the components in medications that have therapeutic effects on the body. They are responsible for the desired pharmacological actions and are crucial for the efficacy of any medicinal product. This article explores various active ingredients commonly used in medicine, their functions, and the conditions they treat.


PQQ is a redox cofactor that is essential for the proper functioning of several enzymes involved in oxidative metabolism. Structurally, it is a small quinone molecule, which allows it to participate in electron transfer processes. Its function as a cofactor is most notable in the enzyme methylene blue reductase, but it is also associated with other enzymes involved in critical biochemical pathways, including those related to energy metabolism.


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