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Another challenge is the global supply chain management of APIs. Many pharmaceutical companies rely on outsourcing API production to countries with lower manufacturing costs, like India and China. While this practice can reduce costs, it also exposes companies to risks such as supply disruptions, quality control issues, and geopolitical factors. In recent years, the COVID-19 pandemic underscored these vulnerabilities, prompting many companies to seek local production options or diversify their suppliers.
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With the increasing demand for titanium dioxide in various industries, the search for reliable suppliers has become crucial. Among the numerous suppliers in the market, r 996 titanium dioxide suppliers have emerged as one of the leading suppliers in the industry.
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Having thus described the origin and uses of the pigment, we now come to the question, what is lithopone? It is, in short, a chemical compound usually consisting of 30.5 per cent zinc sulphide, 1.5 per cent zinc oxide and 68 per cent barium sulphate, but these proportions vary slightly in the different makes. Lithopone of this composition is sold as the highest grade, either as red seal or green seal, as it best suits the idea of the manufacturer. Many manufacturers, especially in Europe, sell and also export other brands under other seals, containing 24, 20, 18 and as little as 12 per cent of zinc sulphide with very small percentages of zinc oxide, the balance being usually barium sulphate, but sometimes certain portions of China clay or gypsum (calcium sulphate) or whiting (calcium carbonate). Such brands are not a chemical compound, but mechanical mixtures of the chemically compounded lithopone and the admixtures referred to.
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Let’s break the risk down further.
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- In the cosmetics industry, titanium dioxide is used as a sunscreen agent due to its ability to block harmful UV rays
- Lithopone pigment, a vital compound primarily composed of zinc sulfide and barium sulfate, has revolutionized various manufacturing sectors due to its exceptional properties. This unique blend offers high refractive index values, making it an indispensable material for achieving brightness and opacity in paints, plastics, and printing inks. As industries continue to evolve, the demand for lithopone pigment remains steady, prompting the establishment of numerous factories dedicated to its production.
Titanium dioxide (TiO2) is commonly applied to enhance the white colour and brightness of food products. TiO2 is also used as white pigment in other products such as toothpaste. A small fraction of the pigment is known to be present as nanoparticles (NPs). Recent studies with TiO2 NPs indicate that these particles can have toxic effects. In this paper, we aimed to estimate the oral intake of TiO2 and its NPs from food, food supplements and toothpaste in the Dutch population aged 2 to over 70 years by combining data on food consumption and supplement intake with concentrations of Ti and TiO2 NPs in food products and supplements. For children aged 2-6 years, additional intake via ingestion of toothpaste was estimated. The mean long-term intake to TiO2 ranges from 0.06 mg/kg bw/day in elderly (70+), 0.17 mg/kg bw/day for 7-69-year-old people, to 0.67 mg/kg bw/day in children (2-6 year old). The estimated mean intake of TiO2 NPs ranges from 0.19 μg/kg bw/day in elderly, 0.55 μg/kg bw/day for 7-69-year-old people, to 2.16 μg/kg bw/day in young children. Ninety-fifth percentile (P95) values are 0.74, 1.61 and 4.16 μg/kg bw/day, respectively. The products contributing most to the TiO2 intake are toothpaste (in young children only), candy, coffee creamer, fine bakery wares and sauces. In a separate publication, the results are used to evaluate whether the presence of TiO2 NPs in these products can pose a human health risk.
The main food categories contributing to dietary exposure of E171 are fine bakery wares, soups, broths and sauces (for infants, toddlers and adolescents); and soups, broths, sauces, salads and savoury based sandwich spreads (for children, adults and the elderly). Processed nuts are also a main contributing food category for adults and the elderly.
Pigmentary TiO2 particles are approximately 200-350nm in dimension and this form accounts for 98 percent of total production. It is used mainly for light scattering and surface opacity applications. It is used as a base for various colour paints or as a standalone ‘brilliant’ white.
TiO2 has been well accepted in the food industry and can be found as the E171 additive in various food products, mainly for whitening and texture. It is present in some cottage and Mozzarella cheeses, horseradish cream and sauces, lemon curd, and in low-fat products such as skimmed milk and ice-cream. Even if the product is labelled as containing E171, no information is usually given about the quantity, particle size and particle structure. FDA claims that TiO2 may be safely used as a colour additive for colouring foods in quantities up to 1 % by weight of the food. Interestingly, TiO2 is frequently declared as a “natural colouring agent” and is therefore well accepted by consumers.
The price trendss for titanium dioxide kept on the lower side of the scale during the first half of 2023. As the paint and coatings industries reduced their offtakes, the abundant supply of the product in the market led to a fall in prices. The prices also suffered from falling energy costs and declining freight charges. Further, the rising speculations of a global recession caused manufacturers to participate actively in destocking.
- Richard S. Lewis, Hawley's Condensed Chemical Dictionary, Van Nostrand Reinhold, New York, 10th ed., 1993
- Overall, chemical building coatings are an essential component of modern construction projects. By providing protection against the elements, enhancing aesthetics, and improving energy efficiency, these coatings help to ensure that buildings remain functional and visually appealing for years to come. Whether it's a high-rise office building or a residential home, chemical building coatings are a key element in creating durable, sustainable, and beautiful structures.
We apply titanium dioxide to our skin through sunscreens, makeup, lip balms, nail polish, and other cosmetic products.
Lithopone B301, Lithopone B311 powder is widely used in coatings, printing ink, rubber, plastic industry, etc.