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Excipients are often overlooked, yet they significantly impact the overall quality and performance of the medication. For example, in liquid formulations, excipients can help ensure that the active ingredient is evenly distributed throughout the solution, maintaining uniformity in dosages. Additionally, excipients can improve the shelf life of a product by providing stability and protecting active ingredients from degradation due to moisture, heat, or light.
ingredients in pharmaceutical products...
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CoQ10 is a naturally occurring antioxidant found in the cells of the body, mainly in the mitochondria, where it plays a vital role in energy production. It is essential for converting nutrients into ATP (adenosine triphosphate), the energy currency of the cell. Levels of CoQ10 naturally decline with age, which can lead to reduced energy levels and increased fatigue.
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The development process begins with drug discovery, focusing on identifying potential candidates that can effectively target specific biological pathways. During this phase, researchers explore various chemical entities to assess their activity against disease models. Once promising candidates emerge, they advance into preclinical studies, where APIs undergo rigorous testing for pharmacokinetics, pharmacodynamics, and toxicity. These studies ensure that selected APIs have the potential for success in clinical trials.
api drug development...