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Formulation refers to the process of combining APIs with other substances to develop a viable drug product. These additional substances, often referred to as excipients, can include fillers, binders, preservatives, and stabilizers. The formulation is crucial because it determines the drug's stability, absorption, distribution, metabolism, and excretion (ADME) properties.
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Moreover, the addition of calcium not only supports the structural integrity of bones and teeth but also contributes to muscle contraction, neurotransmission, and various enzymatic activities. The synergistic effects of d,l-α-ketoisoleucine and calcium underscore their importance in promoting overall health and well-being.
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Moreover, the relationship between pharmaceutical companies and intermediates manufacturers is often collaborative. These manufacturers work closely with their clients during the drug development process to provide not only the intermediates but also insights into chemical synthesis and process optimization. This collaboration can significantly shorten the time-to-market for new drugs and can also lead to cost savings in the overall manufacturing process. As regulatory hurdles increase, the ability of intermediates manufacturers to navigate complex compliance requirements also becomes a valuable asset for pharmaceutical companies.
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