One of the primary reasons for the utilization of isoflurane in mice is its pharmacokinetics. Isoflurane is quickly absorbed and eliminated from the body due to its low blood-gas partition coefficient. This property allows for rapid adjustments in anesthetic depth, facilitating procedures that require precise control over anesthesia. For researchers, these attributes are particularly important, as they minimize the time mice spend under anesthesia and reduce recovery times, ultimately leading to better outcomes in experimental settings.
Pentoxifylline, a methylxanthine derivative, is primarily known for its ability to improve blood flow and enhance tissue oxygenation. Originally developed in the 1970s, pentoxifylline is utilized to treat various conditions associated with poor blood circulation, making it a valuable agent in the field of medicine.