what is pharmaceutical intermediates

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Atorvastatin, a statin used to lower cholesterol levels, serves as an example of an API in cardiovascular health. This compound inhibits the HMG-CoA reductase enzyme, which plays a critical role in the biosynthesis of cholesterol in the liver. By reducing cholesterol, atorvastatin helps prevent heart disease and stroke, highlighting the role of APIs in managing chronic health conditions.


PQQ may also contribute to cardiovascular health. By reducing oxidative stress and inflammation, PQQ can help protect the heart and blood vessels from damage. Some studies have indicated that PQQ may improve lipid profiles by lowering LDL cholesterol and increasing HDL cholesterol levels. This action can reduce the risk of heart disease and stroke, thereby promoting overall cardiovascular wellness.


Sulphamic acid, scientifically designated as H3NSO3, is an important inorganic compound characterized by its sulfonamide group. This strong acid is a white, crystalline substance that plays a crucial role in various industrial applications, making it a subject of interest for chemists and engineers alike.


The increasing demand for recycling and sustainable materials also influences the field of plastic and polymer additives. The handbook assesses techniques for analyzing additives in recycled plastics and discusses the challenges associated with maintaining performance standards in recycled materials. This insight is pivotal as industries strive for circular economy principles, aiming to repurpose plastic waste without compromising quality.


Regulatory Considerations


In the pharmaceutical industry, the term Active Principle Ingredient (API) holds significant importance as it pertains to the core component of a drug that provides therapeutic effects. Understanding the characteristics, development, and regulatory challenges surrounding APIs is crucial for stakeholders in the healthcare sector, including pharmaceutical manufacturers, healthcare professionals, and patients.


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