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The process of developing an API typically involves several stages, starting with research and development (R&D). This phase includes the identification of potential drug candidates, preclinical studies, and clinical trials to establish safety and efficacy. Once promising candidates are identified, the focus shifts to optimizing the synthesis process to ensure scalability and cost-effectiveness. This often requires collaboration between chemists, biologists, and pharmaceutical scientists to fine-tune the production parameters.


The year 2020 was a year when the global pharmaceutical industry was profoundly affected by the epidemic. It was also a year when China’s API industry withstood the test of fluctuations in the international market.  According to the preliminary statistics of China Chamber of Commerce for Medical Insurance, in 2020, China’s API exports reached us $35.7 billion, another record high, with a year-on-year growth of about 6%.

With the aging population and rising incidences of diseases linked to mitochondrial dysfunction, such as Alzheimer's and Parkinson's, the relevance of compounds like PQQ has become increasingly important. Efforts to understand the optimal dosages, bioavailability, and long-term effects of PQQ supplementation continue to evolve, paving the way for greater insights into its potential as a therapeutic agent.


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5. Environmental Resistance Fillers such as UV stabilizers and antioxidants can extend the lifespan of plastic products by protecting them from degradation due to environmental factors, reducing the need for frequent replacements and thereby minimizing waste.


Another challenge is the global supply chain management of APIs. Many pharmaceutical companies rely on outsourcing API production to countries with lower manufacturing costs, like India and China. While this practice can reduce costs, it also exposes companies to risks such as supply disruptions, quality control issues, and geopolitical factors. In recent years, the COVID-19 pandemic underscored these vulnerabilities, prompting many companies to seek local production options or diversify their suppliers.


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In addition to coagulants, flocculants are used to enhance the settling of these aggregates. Polymers, typically synthetic compounds, serve this purpose effectively by binding particles together, resulting in larger, heavier flocs that settle out of the water column more readily. This step not only aids in solids removal but also reduces the volume of sludge that must be processed further.


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