In summary, the cost of isoflurane per bottle is influenced by multiple factors, including the manufacturer, geographic location, purchase volume, market dynamics, and regulatory considerations. As an essential agent in anesthesia practice, its price may fluctuate, but the benefits it provides in terms of patient safety and operational efficiency often justify the expenditure. Healthcare providers must evaluate the cost of isoflurane not only from a financial perspective but also considering its effectiveness in enhancing surgical outcomes and patient care.