cas：23111-00-4

Understanding CAS Registry Number 23111-00-4 and Its Significance

The Chemical Abstracts Service (CAS) registry number serves as a unique identifier for chemical substances, facilitating the cataloging and retrieval of chemical information in scientific literature and databases. CAS number 23111-00-4 refers to a specific compound known as Phenoxymethylpenicillin, commonly known as penicillin V. This antibiotic plays a critical role in combating bacterial infections and has been widely used in clinical settings.

Chemical Structure and Properties

Penicillin V, the compound associated with CAS 23111-00-4, is a beta-lactam antibiotic, which means it contains a beta-lactam ring in its molecular structure. The presence of this ring is fundamental to the antibiotic activity of penicillin. The molecular formula for Penicillin V is C16H17N2O5S, and its structural configuration allows it to effectively inhibit the synthesis of bacterial cell walls. This leads to the cessation of growth and ultimately the death of susceptible bacteria.

Penicillin V is generally administered orally, which distinguishes it from its counterpart, Penicillin G, that is often given via injection. Its relative stability in the acidic environment of the stomach makes it a preferred choice for outpatient treatment of various infections, particularly those caused by Streptococcus species.

The mechanism of action of Penicillin V involves the inhibition of transpeptidase, an enzyme crucial for the cross-linking of peptidoglycan layers in bacterial cell walls. By binding to this enzyme, Penicillin V disrupts the structural integrity of the bacteria, rendering them unable to maintain their cell wall. This vulnerability allows osmotic pressure to cause the cells to burst, resulting in bacterial lysis.

Due to its effectiveness against a range of gram-positive bacteria, Penicillin V is commonly prescribed for conditions such as streptococcal pharyngitis (strep throat), skin infections, and some dental infections. However, it is important to note that its efficacy against gram-negative bacteria is limited, as these organisms possess a more complex outer cell membrane that provides an additional barrier to antibiotic penetration.

Clinical Uses and Resistance Issues

Despite the success of Penicillin V in treating bacterial infections, the rise of antibiotic resistance has become a significant challenge. Overuse and misuse of antibiotics have led to the emergence of resistant strains of bacteria, limiting the effectiveness of Penicillin V and other antibiotics. In particular, strains of Streptococcus pneumoniae and Staphylococcus aureus have shown resistance, prompting the need for alternative treatment options and new research into antibiotic development.

To mitigate resistance issues, healthcare practitioners emphasize the importance of appropriate prescribing practices. This includes accurate diagnosis, proper dosing, and adhering to treatment courses to ensure complete eradication of the bacteria and decrease the chance of resistance development.

Conclusion

CAS number 23111-00-4 signifies more than just a chemical compound; it represents a critical tool in the ongoing battle against bacterial infections. Penicillin V has provided extensive therapeutic benefits since its discovery, enabling effective treatment for various infections. However, its continued success hinges on responsible use and the ongoing research into combating antibiotic resistance.

As we advance in our understanding of microbiology and pharmacology, the challenge remains to preserve the efficacy of existing antibiotics while developing new alternatives. Awareness and education surrounding antibiotics, such as Penicillin V, are paramount in ensuring their effectiveness for future generations. The journey of antibiotics is far from over, and understanding compounds like Penicillin V is crucial for innovative approaches in the field of medicine.