CAS Number 23111-00-4 An Overview of 2-Nitrobenzaldehyde
The chemical compound identified by the CAS number 23111-00-4 is commonly known as 2-Nitrobenzaldehyde. This organic compound is a derivative of benzaldehyde where a nitro group replaces one hydrogen atom on the benzene ring. The molecular formula for 2-Nitrobenzaldehyde is C7H5NO3, and it has a molar mass of approximately 151.12 g/mol. This compound is of significant interest in various fields, including organic chemistry, pharmaceuticals, and material science.
Chemical Structure and Properties
2-Nitrobenzaldehyde features a nitro group (-NO2) on the second carbon atom of the aromatic ring, making it an ortho-nitro derivative. The presence of the nitro group affects the electronic properties of the compound, resulting in a molecule that is generally more reactive than benzaldehyde. The nitro functional group is known for its strong electron-withdrawing properties, which can enhance the electrophilicity of the benzaldehyde group.
In terms of physical properties, 2-Nitrobenzaldehyde is a yellow solid at room temperature with a melting point of about 42-45 °C. It is slightly soluble in water but more soluble in organic solvents such as ethanol and acetone. The compound is also characterized by its distinctive aromatic odor, typical of many benzaldehyde derivatives.
Synthesis of 2-Nitrobenzaldehyde
CAS Number 23111-00-4 An Overview of 2-Nitrobenzaldehyde
Another synthetic route involves the direct reduction of 2-Nitrobenzyl alcohol, which is prepared from the nitration of benzyl alcohol. This route is often favored in laboratory settings due to its straightforward approach and comparatively high yields.
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Applications
2-Nitrobenzaldehyde has various applications across several industries. In organic synthesis, it serves as an important intermediate for the production of numerous pharmaceuticals, dyes, and agrochemicals. The reactivity of the nitro group allows for further functionalization, enabling chemists to create more complex molecules tailored to specific applications.
In addition to its usefulness in chemical synthesis, 2-Nitrobenzaldehyde is utilized in the manufacture of specialized dyes and pigments. The compound's unique coloration and functional properties make it a valuable component in the formulation of colorants for textiles and plastics.
Furthermore, 2-Nitrobenzaldehyde has attracted attention in medicinal chemistry for its potential pharmacological activities. Research has shown that derivatives of nitrobenzaldehyde can exhibit antibacterial, antifungal, and anticancer properties. Scientists continue to explore its biological activity, seeking to tap into its therapeutic potential through the development of novel compounds.
Safety and Handling
As with many chemical compounds, proper safety precautions should be taken when working with 2-Nitrobenzaldehyde. It is advisable to handle the compound in a fume hood while wearing appropriate protective gear, including gloves and goggles. The compound is classified as a hazardous material and may cause irritation upon contact with skin or eyes. Additionally, inhalation of dust or vapors should be avoided, as it may lead to respiratory issues.
In conclusion, 2-Nitrobenzaldehyde (CAS 23111-00-4) is a versatile and important chemical compound in the realm of organic chemistry. Its unique properties, methods of synthesis, and broad applications across various industries underscore its significance in both research and practical applications. As studies continue to unveil its potential, 2-Nitrobenzaldehyde remains a focal point for innovation in chemical synthesis and medicinal research.