6-Chloro-3-Methyluracil (CAS No. 4318-56-3) is an industrial-grade chemical compound used in various chemical and pharmaceutical applications. As a derivative of uracil, this compound possesses unique properties that make it valuable for synthesis and material development. This article explores the applications, properties, and industrial significance of 6-Chloro-3-Methyluracil.
Chemical Properties of 6-Chloro-3-Methyluracil
Molecular Formula: C5H5ClN2O2
Molecular Weight: 160.56 g/mol
Appearance: White to off-white crystalline powder
Solubility: Soluble in organic solvents, slightly soluble in water
Stability: Stable under normal storage conditions, but should be kept away from strong oxidizing agents
This compound is known for its chemical reactivity, especially in nucleophilic substitution reactions, making it useful in synthetic chemistry.
Industrial Applications of 6-Chloro-3-Methyluracil
- Intermedi Farmaceutici
6-Chloro-3-Methyluracil serves as a crucial intermediate in pharmaceutical synthesis. It is used in the production of various drugs, particularly those related to:
Antiviral agents: Its uracil structure plays a role in modifying nucleoside analogs used in antiviral treatments.
Anticancer compounds: Some research explores uracil derivatives as precursors in chemotherapeutic agents.
Cardiovascular medications: It is a key intermediate in some drugs aimed at regulating blood pressure and cardiac function.
- Agrochemical Applications
This compound plays an essential role in agrochemical formulations, particularly in:
Herbicide synthesis: 6-Chloro-3-Methyluracil is used as a precursor in certain herbicides that inhibit plant growth by interfering with nucleic acid metabolism.
Pesticide development: Some derivatives are explored for pest control applications, ensuring effective crop protection.
- Specialty Chemical Synthesis
6-Chloro-3-Methyluracil is widely utilized in organic synthesis, offering reactivity for:
Heterocyclic compound development: Its uracil core is a useful scaffold in various chemical modifications.
Material science applications: Used in the synthesis of specialized resins, coatings, and advanced materials requiring high thermal and chemical resistance.
Handling and Safety Considerations of 6-Chloro-3-Methyluracil
As an industrial-grade chemical, 6-Chloro-3-Methyluracil requires careful handling to ensure safety and compliance with industry regulations.
Storage: Keep in a cool, dry, and well-ventilated area, away from incompatible substances.
Handling Precautions: Use protective gloves, eyewear, and appropriate lab attire when handling the compound.
Disposal: Follow local environmental regulations for the safe disposal of chemical waste.
Considerations in Industrial Production and Handling for 6-Chloro-3-Methyluracil
When it comes to the industrial production of 6 - chloro - 3 - methyluracil, specific processes are employed to ensure high - quality output. The manufacturing process often starts with the selection of appropriate starting materials and reaction conditions. Since it is an industrial - grade product, cost - effectiveness and scalability are important factors. The production facilities need to adhere to strict safety and environmental regulations due to the nature of the chemical reactions involved.
During handling, workers must take precautions as 6 - chloro - 3 - methyluracil may pose certain health risks. It is classified with risk terms such as R36/37/38, indicating that it may cause irritation to eyes, respiratory system, and skin. Therefore, proper personal protective equipment, like gloves, goggles, and respirators, should be worn. Additionally, storage conditions need to be carefully controlled to prevent degradation or unwanted reactions.
6-Chloro-3-Methyluracil is a versatile and valuable industrial chemical with applications in pharmaceuticals, agrochemicals, and material sciences. With its strong reactivity and stability, it continues to be a critical component in chemical synthesis and advanced manufacturing processes. As industries evolve, the demand for high-purity and efficiently synthesized uracil derivatives like 6-Chloro-3-Methyluracil is expected to increase, reinforcing its importance in modern industrial chemistry.