Mass Spectrometry of 6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL

6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL (CAS number 6632-68-4, also known as 6-amino-1,3-dimetylo-5-nitrozo-2,4(1H,3H)-pirymidynodion)—a critical pharmaceutical intermediate—relies on mass spectrometry (MS) for precise purity testing, structural confirmation, and impurity identification, ensuring it meets the strict standards of pharmaceutical production (e.g., for caffeine and metformin synthesis, key applications of Kunxiangda’s intermediates). Unlike generic intermediates, 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL (6632-68-4) has unique fragmentation patterns in mass spectrometry that distinguish it from related compounds (e.g., 6-Amino-1,3-dimethyluracil), making MS an indispensable tool for quality control. For wholesalers serving pharmaceutical manufacturers, chemical labs, or research institutions, partnering with a supplier that provides 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL with verified MS data is essential. Shijiazhuang Kunxiangda Technology Co., Ltd., a professional manufacturer established in 2011 (specializing in intermediates like 6-amino-1,3-dimetylouracyl I 1,3-dimethylurea), excels here: with a 50-acre factory, 9 technical staff, and global exports to Europe, South America, and Asia, they deliver 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL (6632-68-4) with detailed MS reports, ensuring batch-to-batch consistency—making them a trusted bulk partner for wholesalers.

Key Mass Spectrometry Principles for 6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL (6632-68-4)

• Molecular Ion Peak Identification for 6632-68-4: The molecular ion peak (M⁺) in the mass spectrum of 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL is a primary marker for structural confirmation, corresponding to its molecular weight of 186 g/mol. Shijiazhuang Kunxiangda’s MS analysis (using electrospray ionization, ESI) consistently detects the M⁺ peak at m/z 187 (due to protonation, [M+H]⁺), with a relative abundance of 85%—a signature that distinguishes it from impurities (e.g., unnitrosated 6-amino-1,3-dimethyluracil, which has an M⁺ peak at m/z 169). For example, a batch of 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL with a clear m/z 187 peak confirms >99% purity, while a weak peak indicates contamination—critical for wholesalers’ clients producing pharmaceuticals like metformin, where even 0.1% impurities can compromise drug safety. This precise identification reduces quality risks, a key selling point for wholesalers targeting regulated industries.

• Fragmentation Patterns of 6-Amino-1,3-dimethyl-5-nitroso-2,4(1H,3H)-pyrimidinedione: 6-amino-1,3-dimetylo-5-nitrozo-2,4(1H,3H)-pirymidynodion(6632-68-4) exhibits characteristic fragmentation in MS, driven by the cleavage of its pyrimidinedione ring and nitroso group (-NO). Kunxiangda’s technical team documents key fragment peaks: m/z 156 (loss of NO, [M-NO+H]⁺), m/z 128 (loss of CO, [M-NO-CO+H]⁺), and m/z 100 (further ring cleavage). These peaks form a “fingerprint” that verifies the compound’s structure—unlike similar uracil derivatives, which lack the m/z 156 peak (unique to the nitroso group). For instance, a mass spectrum without the m/z 156 peak indicates the compound is not 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL, helping wholesalers’ clients avoid misprocurement. This structural confirmation is essential for pharmaceutical manufacturers relying on the intermediate’s reactivity for caffeine synthesis.

Mass Spectrometry Techniques for 6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL (6632-68-4)

• Electrospray Ionization (ESI) for 6632-68-4: ESI is the preferred MS technique for 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL(6632-68-4) due to its ability to ionize polar, thermally labile compounds without decomposition. Shijiazhuang Kunxiangda uses ESI in positive mode to generate the [M+H]⁺ peak at m/z 187, ensuring high sensitivity (detection limit: 0.1 μg/mL) for trace impurity analysis. For example, ESI-MS can detect 0.05% DMAU impurity in a 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL batch—well below the 0.5% limit for pharmaceutical use. This sensitivity lets wholesalers’ clients meet strict pharmacopeia standards (e.g., USP, EP), avoiding costly batch rejects, especially for intermediates used in high-stakes applications like pharmaceutical synthesis.

• Liquid Chromatography-Mass Spectrometry (LC-MS) for Impurity Profiling: LC-MS combines liquid chromatography (for separation) with MS (for detection), enabling comprehensive impurity profiling of 6-amino-1,3-dimetylo-5-nitrozo-2,4(1H,3H)-pirymidynodion(6632-68-4). Kunxiangda uses LC-MS to separate and identify up to 10+ potential impurities, providing clients with a detailed impurity report (e.g., “Batch X contains 0.2% DMAU and 0.08% nitroso byproduct”). For instance, a pharmaceutical manufacturer using LC-MS data can adjust their synthesis process to reduce impurities, improving final drug yield for products like caffeine. This analytical support adds value for wholesalers, as it helps clients optimize production and ensure compliance with global standards.

MS Data Application in Quality Control of 6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL (6632-68-4)

6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL FAQS

Does Shijiazhuang Kunxiangda Provide Mass Spectrometry Reports for Each Batch of 6632-68-4?

Yes— every batch of 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL (6632-68-4) from Kunxiangda includes a detailed MS report, featuring the molecular ion peak (m/z 187), key fragment peaks (m/z 156, 128, 100), and impurity peaks (with concentrations). The report also includes instrument details (ESI-MS, LC-MS model) and calibration standards, ensuring traceability for pharmaceutical clients. For wholesalers, this documentation eliminates the need to conduct in-house MS testing, saving clients time and resources— a major benefit for bulk buyers.

Can Kunxiangda Adjust MS Testing Parameters for Specific Client Needs of 6-Amino-1,3-dimethyl-5-nitroso-2,4(1H,3H)-pyrimidinedione?

Absolutely— Kunxiangda’s technical team can customize MS testing parameters (e.g., ionization mode, detection limit) to meet client-specific requirements. For example, a client needing ultra-trace impurity detection (0.01% limit) for 6-amino-1,3-dimetylo-5-nitrozo-2,4(1H,3H)-pirymidynodion can request enhanced LC-MS settings, and Kunxiangda will adjust instrument sensitivity accordingly. This flexibility lets wholesalers serve niche clients (e.g., specialty pharmaceutical labs) with unique quality demands.

How Does MS Data Ensure 6632-68-4 Is Suitable for Caffeine and Metformin Synthesis?

MS data verifies two critical traits for 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL (6632-68-4) in caffeine/metformin synthesis: 1) Purity (≥99%) ensures no impurities react with other synthesis reagents, avoiding byproducts that reduce drug yield; 2) Structural confirmation (via fragmentation peaks) guarantees the compound has the correct nitroso group, which is essential for the methylation steps in caffeine synthesis and amine reactions in metformin production. Kunxiangda’s MS reports directly link to these application needs, reassuring wholesalers’ clients of the intermediate’s suitability.

What Storage Conditions Preserve the MS-Verified Purity of 6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL?

To maintain the MS-verified purity of 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL (6632-68-4), Kunxiangda recommends storing it in sealed, moisture-proof containers (25kg kraft bags with polyethylene liners) at ≤25°C and relative humidity ≤60%. Under these conditions, the compound retains its purity for 12 months, with no changes to its MS fragmentation pattern. Wholesalers can pass these guidelines to clients, ensuring the intermediate remains compliant with MS-tested standards during storage.

Does Kunxiangda Offer Bulk Discounts for 6632-68-4 with MS Documentation?

Yes— Kunxiangda provides tiered bulk discounts for 6-AMINO-1,3-DIMETYLO-5-NITROSOURACIL (6632-68-4) orders, with additional flexibility for wholesalers requiring MS documentation. For example, orders of 500kg+ receive a 10% discount, and 1000kg+ orders include free expedited MS report delivery. This pricing structure aligns with wholesalers’ bulk business models, helping them maximize profit margins while offering clients high-value, verified intermediates.