Ukuphonononga usetyenziso oluguquguqukayo lwePentoxifylline

Ipentoxifylline, iyeza lodidi lwe-xanthine derivatives, lisetyenziswa ngokubanzi kwiimeko ezahlukeneyo zonyango ngenxa yeempawu zayo ze-vasodilatory kunye ne-rheological. Ukusuka kwizifo ze-vascular peripheral ukuya kwiimeko zedermatological, i-pentoxifylline ifumana izicelo ezininzi kumayeza anamhlanje. Eli nqaku ligocagoca kwiintlobo ezahlukeneyo zokusetyenziswa kwe-pentoxifylline, inika ukukhanya kwiinzuzo zayo zonyango kunye nokubaluleka kweklinikhi.

Izifo ze-Vascular ze-Peripheral

I-Pentoxifylline ye-Pentoxifylline idla ngokumiselwa kubantu abanesifo se-peripheral vascular disease, imeko ebonakala ngokucutheka okanye ukuvaleka kwemithambo yegazi ezingalweni, emilenzeni, okanye kwezinye iindawo zomzimba. Ngokuphucula ukuhamba kwegazi kunye nokuhamba kwegazi kumalungu achaphazelekayo, i-pentoxifylline inceda ukunciphisa iimpawu ezinjengeentlungu, ukuqaqanjelwa, kunye nokuba ndindisholo, ngaloo ndlela iphucula umgangatho wobomi bezigulane ezine-PVD.

I-Intermittent Claudication: I-Intermittent claudication, impawu ye-peripheral artery disease (PAD), ibhekisela kwiintlungu okanye ukunyanzeliswa kwemilenze ngexesha lomsebenzi womzimba ngenxa yokungonelanga kwegazi. I-Pentoxifylline ihlala isetyenziselwa ukulawula i-intermittent claudication ngokunyusa ukuhamba kwegazi kwimisipha echaphazelekayo, ukunciphisa ischemia, kunye nokuphucula ukunyamezela komthambo. Oku kunceda abantu abane-PAD ukuba bazibandakanye kwimisebenzi yomzimba bengakhululeki kangako kunye nokuhamba ngcono.

Iimeko zeDermatological

Izilonda zeVen: I-Pentoxifylline ikwasetyenziswa kunyango lwezilonda ze-venous, ezizizilonda ezivulekileyo ezikhula emilenzeni okanye ezinyaweni ngenxa yokuphazamiseka kokujikeleza kwe-venous. Ngokwandisa ukuhamba kwegazi kunye ne-oksijini yezicubu, i-pentoxifylline ikhuthaza ukuphiliswa kwenxeba kwaye iququzelele ukuvalwa kwezilonda ze-venous. Ukongeza, i-pentoxifylline inokunceda ukunciphisa ukudumba kunye ne-edema ehambelana nezilonda ze-venous, inceda ngakumbi kwinkqubo yokuphilisa.

Ezinye iimeko zonyango

Isifo sezintso eziNgapheliyo (CKD): Ipentoxifylline ubonise isithembiso ekulawulweni kwezifo ezingapheliyo zezintso, ngakumbi kubantu abaneproteinuria kunye nenephropathy ehambelana nayo. Uphononongo lucebisa ukuba i-pentoxifylline inokuba nefuthe lokuchasa ukudumba kunye ne-antifibrotic kwizintso, ekhokelela ekunciphiseni kweproteinuria kunye nokugcinwa kokusebenza kwezintso. Nangona kunjalo, uphando olongezelelweyo luyafuneka ukucacisa ngokupheleleyo indima ye-pentoxifylline kulawulo lwe-CKD.

I-Rheumatologic Disorders: IPentoxifylline iphandiwe ngeziphumo zayo zonyango ezinokuthi zibe khona kwiingxaki ezahlukeneyo ze-rheumatologic, kubandakanya i-rheumatoid arthritis kunye ne-osteoarthritis. Ngelixa iindlela ezichanekileyo zesenzo zingaqondwa ngokupheleleyo, i-pentoxifylline inokusebenzisa i-anti-inflammatory and immunomodulatory effects ezinegalelo ekupheliseni iimpawu kunye nolawulo lwezifo kwezi meko.

Iingcamango zokuvala

Ukuqukumbela, i-pentoxifylline liyeza eliguquguqukayo elinoluhlu olubanzi losetyenziso kumayeza anamhlanje. Ukusuka kwizifo zemithambo yegazi kunye neemeko zedermatological ukuya kwisifo sezintso esinganyangekiyo kunye nokuphazamiseka kwe-rheumatologic, i-pentoxifylline ibonelela ngezibonelelo zonyango kwiimeko ezahlukeneyo zonyango. Ukuba unayo nayiphi na imibuzo malunga ne-pentoxifylline okanye ukufaneleka kwayo kwiimfuno zakho zonyango, nceda ungalibazisi Qhagamshelana nathi. Silapha ukubonelela ngolwazi kunye nenkxaso malunga neli yeza kunye nokufumaneka kwalo kubaboneleli bethu abathembekileyo.