Kwindawo ye-anesthesia, iinzame eziqhubekayo zenziwa ukuphucula ukhuseleko lwesigulane, ukunciphisa imiphumo emibi, kunye nokuphucula amava apheleleyo kuzo zombini izigulane kunye neengcali zonyango. Sevoflurane, isizolisi sokuphefumla, kuye kwavela njengomdlali obalulekileyo ekuphumezeni ezi njongo. Makhe sihlolisise iimpawu kunye neenzuzo ze-sevoflurane njengoko isondela kwisimo seyeza lokuphefumla elifanelekileyo.
Intshayelelo emfutshane yeSevoflurane
I-Sevoflurane iyinxalenye yeklasi ye-halogenated ethers kwaye isetyenziswa ngokubanzi njenge-anesthetic yokuphefumla kwiinkqubo zotyando kunye nezonyango. Eyaziwayo nge-solubility ephantsi ye-gas-gas, i-sevoflurane yenza i-anesthesia ngokukhawuleza ngelixa ivumela ukuvela ngokukhawuleza kwimeko ye-anesthetic. Ezi zakhiwo ezizodwa ziye zafaka isandla ekunyuseni ukuthandwa kwayo kwiindawo ezahlukeneyo zonyango.
Ukuqalisa ngokukhawuleza kunye nokunciphisa
1. Ukuqaliswa kwe-Anesthesia:
Enye yeenzuzo eziphambili ze-sevoflurane kukuqala kwayo ngokukhawuleza kwesenzo. Izigulana ezilawulwa ngamava e-sevoflurane ukufakwa ngokukhawuleza kunye nokukhawuleza kwe-anesthesia, evumela iingcali zonyango ukuba ziqalise iinkqubo ngokukhawuleza. Olu phawu luluncedo ngakumbi kuqhaqho oluthatha ixesha okanye kwiimeko ezingxamisekileyo.
2. Ukuvela kwi-Anesthesia:
Okubaluleke ngokulinganayo kukukwazi kwe-sevoflurane ukuququzelela ukuvela ngokukhawuleza kwimeko ye-anesthetic. Olu phawu lunenzuzo kwizigulana, njengoko lunciphisa ixesha lokubuyisela, lunciphisa iziphumo ebezingalindelekanga zasemva kotyando, kwaye luvumela inguqu ekhawulezileyo yesigulane kwizibonelelo zonyango.
I-Metabolism encinci kunye neGas ephantsi ye-Solubility yeGas
1. Imetabolism:
Sevoflurane ibalasele kwimetabolism yayo encinci emzimbeni. Olu phawu lunciphisa umngcipheko wokuvelisa i-metabolites eyingozi, igalelo kwiprofayili yokhuseleko jikelele ye-anesthetic. Ukukwazi ukwenza i-biotransformation encinci yokwandisa ukuqikelelwa kweziphumo zayo.
2. Ukunyibilika kweGas-Gas:
I-solubility ephantsi yegazi-gas ye-sevoflurane ivumela ukulingana okukhawulezayo phakathi kwe-alveoli kunye negazi. Oku kubangela ukufakwa ngokukhawuleza kwe-anesthesia kunye nokubuyisela ngokukhawuleza emva kokuyeka. I-solubility ephantsi iphinde ibe negalelo kulawulo oluchanekileyo lobunzulu be-anesthetic ngexesha leenkqubo.
Ukuzinza kwentliziyo
Ukugcina uzinzo lwe-cardiovascular is a particment of anesthesia. I-Sevoflurane ibonise imiphumo emihle kwiiparamitha ze-cardiovascular, inika iphrofayili ezinzileyo ye-hemodynamic ngexesha le-anesthesia. Oku kubaluleke ngakumbi kwizigulane ezinenkxalabo ye-cardiovascular okanye abo baphantsi kweenkqubo zotyando ezinzima.
Ukusebenziseka okubanzi kunye noKuguquguquka
1. Ukusetyenziswa kwabantwana:
I-Sevoflurane ifaneleke kakuhle kwizigulane zabantwana ngenxa yevumba elimnandi, ukuqala ngokukhawuleza, kunye nokulula kolawulo. Ukuthandwa kwayo kwi-anesthesia yabantwana ikhulile, iyenza ibe yinto ekhethwayo yotyando ebantwaneni.
2. Abemi baBantu abadala kunye nabaseGeriatric:
Ngaphandle kokusetyenziswa kwabantwana, ukuguquguquka kwe-sevoflurane kunwenwela kubantu abadala kunye nakwabantu abadala, oko kuyenza ibe lukhetho oluxabisekileyo kumaqela ahlukeneyo obudala. Ukusetyenziswa kwayo ngokubanzi kunegalelo ekwamkelweni kwayo ngokubanzi kwiindawo ezahlukeneyo zonyango.
Ukuqukumbela
Ukuqukumbela, i-sevoflurane iye yavela njengephambili kukhangelo lwe-anesthetic efanelekileyo yokuphefumla. Ngokuqala kwayo ngokukhawuleza kunye nokunciphisa, i-metabolism encinci, i-solubility ephantsi ye-gas-gas, kunye nokuzinza kwe-cardiovascular stability, i-sevoflurane inikeza ukudibanisa kweempawu ezijongene neenkxalabo eziphambili kulawulo lwe-anesthesia. Ukusebenziseka kwayo okubanzi ngakumbi kuqinisa indawo yayo njengokhetho lokuya kubasebenzi bezonyango kwiingcali ezahlukeneyo.
Ukuba unomdla wokufaka i-sevoflurane kunyango lwakho, nceda ungalibazisi Qhagamshelana nathi. Njengomthengisi othembekileyo, sizibophelele ekuboneleleni ngamayeza akumgangatho ophezulu kunye neemveliso zonyango ukuhlangabezana neemfuno zabasebenzi bezempilo. Phakamisa ukuziqhelanisa kwakho ne-anesthesia ngezibonelelo ezibonelelwa yi-sevoflurane.
Ixesha lokuposa: Jan-13-2024