Theophylline ndi chiyani?

Theophylline, membala wa gulu la xanthine la mankhwala, amatenga gawo lofunikira pakuwongolera kupuma, makamaka mphumu ndi matenda osachiritsika a m'mapapo (COPD). Mankhwalawa amagwira ntchito ngati bronchodilator, kupereka mpumulo kwa anthu omwe akuvutika ndi kupuma. Kupitilira pakugwiritsa ntchito kwake pazovuta za kupuma, Theophylline imawonetsanso zotsatira pamtima ndi dongosolo lapakati lamanjenje, ndikupangitsa kuti ikhale mankhwala osunthika pazachipatala.

Kumvetsetsa Theophylline ngati Bronchodilator

Njira ya Bronchodilation

Theophylline imagwira ntchito yake ya bronchodilator popumula ndi kukulitsa njira ya mpweya m'mapapu. Imakwaniritsa izi poletsa zochita za phosphodiesterase, puloteni yomwe imaphwanya cyclic AMP (cAMP). Kukwera kwa cAMP kumapangitsa kuti minofu ikhale yosalala, zomwe zimapangitsa kuti njira za mpweya wa bronchial ziwonjezeke. Makinawa amathandizira kuyenda bwino kwa mpweya, kupangitsa kupuma kosavuta kwa anthu omwe ali ndi vuto la kupuma.

Mikhalidwe Yopuma ndi Theophylline

Kugwiritsa ntchito kwakukulu kwa Theophylline kwagona pakuwongolera mphumu ndi COPD. Mu mphumu, imathandizira kuchepetsa bronchoconstriction, pomwe ili mu COPD, imathandizira kuchepetsa kukana kwa mpweya. Theophylline nthawi zambiri amalembedwa pamene ma bronchodilators ena, monga beta-agonists kapena anticholinergics, sangapereke mpumulo wokwanira.

Zotsatira Zowonjezera za Theophylline

Matenda a mtima

Kupatula phindu lake la kupuma, Theophylline imakhudzanso dongosolo la mtima. Ikhoza kulimbikitsa mtima, zomwe zimapangitsa kuti mtima uwonjezeke komanso kugunda kwamphamvu. Izi zimapangitsa kukhala kofunika kuti akatswiri azachipatala aziwunika mosamala odwala, makamaka omwe ali ndi matenda amtima omwe analipo kale, panthawi ya Theophylline.

Zotsatira za Central Nervous System

Theophylline'chikoka chimafikira ku dongosolo lapakati lamanjenje, komwe limatha kulimbikitsa malo opumira muubongo. Kukondoweza kumeneku kumawonjezera mphamvu yopuma, kumathandizira kuti mankhwalawa agwire bwino ntchito pothana ndi vuto la kupuma.

Kuganizira Zachipatala ndi Mlingo

Chithandizo Payekha

Chifukwa cha kusiyana kwa kuyankha kwa odwala ndi kagayidwe kake, mlingo wa Theophylline umafunika munthu payekha. Zinthu monga zaka, kulemera, ndi mankhwala omwe amamwa mankhwala amatha kukhudza momwe thupi limagwirira ntchito Theophylline. Kuwunika pafupipafupi kuchuluka kwa magazi m'magazi ndikofunikira kuti muwonetsetse kuti machiritso agwira ntchito ndikupewa zomwe zingachitike.

Zomwe Zingatheke

Monga mankhwala aliwonse, Theophylline ikhoza kuyambitsa zotsatira zoyipa. Zotsatira zodziwika bwino zimaphatikizapo nseru, mutu, ndi kusowa tulo. Zotsatira zoyipa, monga kugunda kwa mtima mwachangu kapena kukomoka, zimafunikira chithandizo chamankhwala mwachangu.

Mapeto

Pomaliza, ntchito ya Theophylline monga bronchodilator imapangitsa kuti ikhale yofunika kwambiri pakuwongolera kupuma. Kutha kwake kupumula komanso kukulitsa njira zapamlengalenga kumapereka mpumulo kwa anthu omwe akuvutika ndi mphumu ndi COPD. Komabe, akatswiri azachipatala ayenera kukhala tcheru poyang'anira odwala chifukwa cha zomwe zingachitike pamtima komanso pakatikati. Mapulani achipatala payekha komanso kuwunika pafupipafupi kumatsimikizira zotsatira zabwino zochiritsira ndikuchepetsa zotsatira zoyipa.

Kuti mumve zambiri za Theophylline kapena kufunsa za kupezeka kwake, chonde Lumikizanani nafe. Tadzipereka kupereka mankhwala ofunikira komanso chithandizo chamankhwala opuma. Monga othandizira odalirika, timayesetsa kukwaniritsa zosowa zosiyanasiyana za azaumoyo komanso odwala omwe.