Theophylline ni iki?

Theophylline, umunyamuryango wurwego rwibiyobyabwenge rwa xanthine, agira uruhare runini mugucunga imiterere yubuhumekero, cyane cyane asima nindwara zidakira zifata ibihaha (COPD). Iyi miti ikora nka bronchodilator, itanga ihumure kubantu bafite ibibazo byo guhumeka. Usibye gukoreshwa kwambere mubibazo byubuhumekero, Theophylline irerekana kandi ingaruka kumutima no mumyanya mitsi yo hagati, bigatuma iba imiti itandukanye mubihe bimwe na bimwe byubuvuzi.

Gusobanukirwa Theophylline nka Bronchodilator

Uburyo bwa Bronchodilation

Theophylline igira ingaruka za bronchodilator mu kuruhuka no kwagura inzira zo mu bihaha. Irabigeraho ihagarika ibikorwa bya fosifisiyose, enzyme ishinzwe gusenya cyclic AMP (cAMP). Urwego rwo hejuru rwa cAMP ruganisha kuruhura imitsi neza, bikavamo kwaguka kwimyuka ya bronchial. Ubu buryo bworohereza umwuka mwiza, bigatuma guhumeka byoroha kubantu bafite ibibazo byubuhumekero.

Imiterere y'ubuhumekero na Theophylline

Ikoreshwa ryibanze rya Theophylline riri mubuyobozi bwa asima na COPD. Muri asima, ifasha kugabanya bronchoconstriction, mugihe muri COPD, ifasha mukugabanya imyuka ihumeka. Theophylline ikunze gutegekwa mugihe izindi bronchodilator, nka beta-agoniste cyangwa antikolinergique, idashobora gutanga ubutabazi buhagije.

Ingaruka zinyongera za Theophylline

Ingaruka z'umutima

Usibye inyungu zubuhumekero, Theophylline inagira ingaruka kumitsi yumutima. Irashobora gukangura umutima, biganisha ku kwiyongera k'umutima n'imbaraga zo kwikuramo. Ibi bituma ari ngombwa ko inzobere mu buvuzi zikurikirana neza abarwayi, cyane cyane abafite ibibazo by’umutima byahozeho, mu gihe cyo kuvura Theophylline.

Ingaruka zo hagati ya sisitemu yo hagati

Theophylline'Ingaruka zigera no kuri sisitemu yo hagati, aho ishobora gukangura imyanya y'ubuhumekero mu bwonko. Uku kubyutsa byongera imbaraga zo guhumeka, bigira uruhare mu miti ikora neza mugukemura ibibazo byubuhumekero.

Ibitekerezo bya Clinical na Dosage

Umuti ku giti cye

Bitewe nuburyo butandukanye mubisubizo byabarwayi hamwe na metabolism, dosiye ya Theophylline isaba kugiti cye. Ibintu nkimyaka, uburemere, hamwe nubuvuzi bujyanye bishobora guhindura uburyo umubiri utunganya Theophylline. Gukurikirana buri gihe urwego rwamaraso ningirakamaro kugirango habeho kuvura neza mugihe wirinze uburozi.

Ingaruka Zishobora Kuruhande

Kimwe n'imiti iyo ari yo yose, Theophylline irashobora gutera ingaruka. Ingaruka zisanzwe zirimo isesemi, kubabara umutwe, no kudasinzira. Ingaruka zikomeye, nk'umuvuduko ukabije w'umutima cyangwa gufatwa, zisaba ubuvuzi bwihuse.

Umwanzuro

Mu gusoza, uruhare rwa Theophylline nka bronchodilator rugira umutungo wingenzi mugucunga imiterere yubuhumekero. Ubushobozi bwayo bwo kuruhuka no kwagura inzira zumuyaga bitanga ihumure kubantu barwana na asima na COPD. Nyamara, inzobere mu buvuzi zigomba kuba maso mu gukurikirana abarwayi bitewe n’ingaruka zishobora guterwa n'umutima n'imitsi. Gahunda yo kuvura kugiti cyawe hamwe nisuzuma risanzwe byemeza uburyo bwiza bwo kuvura mugihe hagabanijwe ingaruka mbi.

Kubindi bisobanuro bijyanye na Theophylline cyangwa kubaza kuboneka, nyamuneka twandikire. Twiyemeje gutanga imiti yingenzi ninkunga yubuzima bwubuhumekero. Nkumutanga wizewe, duharanira guhaza ibyifuzo bitandukanye byabatanga ubuvuzi ndetse nabarwayi kimwe.