Testosterone itera kanseri ya prostate mu mbeba

Nk’uko ubushakashatsi bushya bwasohotse mu kinyamakuru cy’umuryango wa Endocrine bubitangaza, umushakashatsi yasanze testosterone yongera ibyago byo kubyimba prostate kandi byongera ingaruka ziterwa n’imiti ya kanseri itera kanseri ku mbeba. Yasabye abagabo batigeze basuzumwa na hypogonadism Witondere igihe utanga imiti ya testosterone. Endocrinology.
Mu myaka icumi ishize, ikoreshwa rya testosterone ryiyongereye cyane mu bagabo bakuze bashaka kongera imbaraga no kumva bakiri bato. Ubushakashatsi bwasohotse mu kinyamakuru cya Clinical Endocrinology na Metabolism bwerekanye ko nubwo hari impungenge z’ingaruka zishobora guterwa n’umutima n’imitsi, umubare w’abagabo b’abanyamerika batangiye kuvura testosterone wikubye hafi kane kuva mu 2000.
The Endocrine Society’s clinical practice guidelines for the treatment of testosterone in adult men recommend that testosterone be prescribed only for men with significantly low hormone levels, decreased libido, erectile dysfunction, or other symptoms of hypogonadism. Online: http://www.endocrine.org/~/ media/endosociety/Files/Publications/Clinical%20Practice%20Guidelines/FINAL-Androgens-in-Men-Standalone.pdf
Umwanditsi w'ubwo bushakashatsi na Dr. Maarten C. Bosland wo muri DVSc wo muri kaminuza ya Illinois i Chicago yagize ati: "Ubu bushakashatsi bwerekana ko testosterone ubwayo ari kanseri idakomeye mu mbeba z'abagabo." Ati: “Iyo ihujwe n’imiti ya kanseri, testosterone ikora ibidukikije bikwiye kugira ngo ikibyimba gikure. Niba ubu bushakashatsi nk'ubwo bwaragaragaye mu bantu, ibibazo by'ubuzima rusange bizaba impamvu ikomeye. ”
Ubushakashatsi bubiri bwakorewe ubushakashatsi bwasuzumye indwara ya kanseri ya prostate ku mbeba. Imbeba zahawe testosterone ikoresheje igikoresho gihoraho-kirekura. Mbere yo gutera testosterone mu mbeba, inyamaswa zimwe na zimwe zatewe imiti ya kanseri N-nitroso-N-methylurea (MNU). Izi mbeba zagereranijwe nitsinda rishinzwe kugenzura ryakiriye MNU ariko ryashizemo ibikoresho byubusa-birekura.
Imbeba zabonye testosterone idafite imiti ya kanseri, 10% kugeza 18% byanduye kanseri ya prostate. Kuvura testosterone yonyine ntabwo byateye ibibyimba byihariye ahandi hantu, ariko ugereranije nimbeba zo kugenzura, byatumye ubwiyongere bukabije bw’imbeba zifite ibibyimba bibi ku rubuga urwo arirwo rwose. Iyo imbeba zanduye testosterone na kanseri, ubu buvuzi butera 50% kugeza kuri 71% byimbeba kurwara kanseri ya prostate. Nubwo imisemburo ya hormone iba mike cyane kuburyo itongera urugero rwa testosterone mumaraso, kimwe cya kabiri cyimbeba ziracyafite ibibyimba bya prostate. Amatungo ahura n’imiti ya kanseri ariko ntabwo yatewe na testosterone ntabwo yigeze arwara kanseri ya prostate.
Boslan yagize ati: "Kubera ko iterambere ry'ubuvuzi bwa testosterone ari shyashya, kandi kanseri ya prostate ni indwara igenda ikura buhoro buhoro, kuri ubu nta makuru yerekana niba testosterone yongera ibyago byo kurwara kanseri ya prostate ku bantu". Ati: “Nubwo ubushakashatsi bwakozwe n'abantu bwakozwe, ni byiza kugabanya imiti ya testosterone ku bagabo bafite hypogonadism ivura indwara, kandi tukirinda abagabo gukoresha testosterone mu buryo butari ubuvuzi, harimo no gukemura ibimenyetso bisanzwe byo gusaza.”
Ubushakashatsi bwiswe “Ubuvuzi bwa testosterone ni uburyo bwiza bwo gutera ibibyimba kuri prostate” byasohotse ku rubuga mbere yo gucapa.
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