Maererano nekuongorora kutsva kwakabudiswa mu Journal of the Endocrine Society, mumwe muongorori akawana kuti testosterone inowedzera njodzi yeprostate tumors uye inowedzera migumisiro yecarcinogenic chemical exposure mumakonzo. Akakurudzira varume vasina kuonekwa kuti vane hypogonadism Iva vakangwarira paunenge uchipa testosterone therapy. Endocrinology.
Mumakore gumi apfuura, kushandiswa kwe testosterone kwakawedzera pakati pevarume vakwegura vachitsvaka kuwedzera simba uye kunzwa vaduku. Chidzidzo chakabudiswa mu Journal of Clinical Endocrinology uye Metabolism chakawana kuti pasinei nekunetseka pamusoro penjodzi dzemwoyo, nhamba yevarume veAmerica vanotanga testosterone therapy yakawedzera zvakapetwa kana kubva 2000.
The Endocrine Society’s clinical practice guidelines for the treatment of testosterone in adult men recommend that testosterone be prescribed only for men with significantly low hormone levels, decreased libido, erectile dysfunction, or other symptoms of hypogonadism. Online: http://www.endocrine.org/~/ media/endosociety/Files/Publications/Clinical%20Practice%20Guidelines/FINAL-Androgens-in-Men-Standalone.pdf
"Ichi chidzidzo chinoratidza kuti testosterone pachayo inokonzerwa nekenza isina simba mumakonzo evarume," akadaro munyori wekudzidza uye Dr. Maarten C. Bosland weDVSc kubva kuYunivhesiti yeIllinois kuChicago. “Kana yakasanganiswa nemakemikari ecarcinogenic, testosterone inogadzira nzvimbo yakakodzera yekukura kwebundu. Kana zviwanwa zvimwe chete izvi zvikaiswa muvanhu, ipapo zvinetso zvoutano hwavose zvichava chisakiso chakakomba.”
Zvidzidzo zviviri zvekupindura zvedosi zvakaongorora chiitiko chegomarara reprostate mumakonzo. Makonzo akapihwa testosterone kuburikidza neyakagadzika-kuburitswa implant mudziyo. Asati apinza testosterone mumakonzo, dzimwe mhuka dzakabayiwa nekemikari yecarcinogenic N-nitroso-N-methylurea (MNU). Aya makonzo akafananidzwa neboka rekutonga rakagamuchira MNU asi rakaisa chinhu chisina chinhu-chakaburitswa-chinoburitsa.
Pakati pemakonzo akagamuchira testosterone pasina kemikari yecarcinogenic, 10% kusvika 18% yakagadzira kenza yeprostate. Kurapa kweTesttosterone chete hakuna kukonzera mamota chaiwo mune dzimwe nzvimbo, asi kana ichienzaniswa nemakonzo ekudzora, yakakonzera kuwedzera kukuru kwenhamba yemakonzo ane mamota akashata pane chero saiti. Kana makonzo akafumurwa kune testosterone necarcinogens, kurapwa uku kunokonzera 50% kusvika 71% yemakonzo kuita cancer yeprostate. Kunyange kana iyo hormone dose yakaderera zvikuru kuti iwedzere chiyero che testosterone muropa, hafu yemakonzo ichiri kutambura neprostate tumors. Mhuka dzakafumurwa kumakemikari ecarcinogenic asi kwete kune testosterone hadzina kuita kenza yeprostate.
"Nemhaka yekuti kukwidziridzwa kwe testosterone therapy kutsva, uye kenza yeprostate chirwere chinokura zvishoma nezvishoma, parizvino hapana data yekuona kana testosterone inowedzera njodzi yekenza yeprostate muvanhu," akadaro Boslan. "Kunyangwe zvidzidzo zvevanhu zvakaitwa, zvine hungwaru kudzikamisa testosterone kuvarume vane symptomatic kliniki hypogonadism, uye kudzivirira varume kushandisa testosterone kune zvisiri zvekurapa zvinangwa, kusanganisira kugadzirisa zvakajairwa zviratidzo zvekuchembera."
Chidzidzo chakanzi "Testosterone therapy inobudirira bundu kusimudzira yemakonzo prostate" yakaburitswa online isati yadhindwa.
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Nguva yekutumira: Sep-09-2021