E tusa ai ma se suʻesuʻega fou na lolomiina i le Journal of the Endocrine Society, na maua ai e se tagata suʻesuʻe o le testosterone e faʻateleina ai le lamatiaga o le prostate tuma ma faʻateleina ai aʻafiaga o faʻamaʻi pipisi o le carcinogenic i isumu. Na ia una'ia alii e le'i maua i le hypogonadism Ia fa'aeteete pe a fa'atino togafitiga o le testosterone. Endocrinology.
I le sefulu tausaga talu ai, o le faʻaaogaina o le testosterone ua faʻateleina i tama matutua o loʻo taumafai e faʻateleina le malosi ma lagona le laʻititi. O se suʻesuʻega na lomia i le Journal of Clinical Endocrinology and Metabolism na maua ai e ui lava i popolega e uiga i aʻafiaga o le cardiovascular, o le aofaʻi o tamaloloa Amerika e amata togafitiga testosterone ua toetoe lava faʻalua talu mai le 2000.
The Endocrine Society’s clinical practice guidelines for the treatment of testosterone in adult men recommend that testosterone be prescribed only for men with significantly low hormone levels, decreased libido, erectile dysfunction, or other symptoms of hypogonadism. Online: http://www.endocrine.org/~/ media/endosociety/Files/Publications/Clinical%20Practice%20Guidelines/FINAL-Androgens-in-Men-Standalone.pdf
"O lenei suʻesuʻega e faʻaalia ai o le testosterone lava ia o se faʻamaʻi vaivai i tamaʻi iole," o le tala lea a le tusitala o le suʻesuʻega ma Dr. Maarten C. Bosland o DVSc mai le Iunivesite o Ilinoi i Chicago. "Pe a tuʻufaʻatasia ma vailaʻau faʻamaʻi, o le testosterone e maua ai se siosiomaga talafeagai mo le atinaʻeina o le tuma. Afai o nei lava suʻesuʻega e faʻamautu i tagata, ona avea lea o faʻafitauli o le soifua maloloina lautele ma mafuaʻaga ogaoga.
E lua su'esu'ega tali atu na su'esu'eina le a'afiaga o le kanesa prostate i isumu. Na tu'uina atu i iole le testosterone e ala i se masini fa'apipi'i fa'aola. Aʻo leʻi tuiina le testosterone i isumu, o nisi o manu na tui ile vailaʻau faʻamaʻi o le N-nitroso-N-methylurea (MNU). O nei iole na fa'atusaina ma se vaega fa'atonutonu na maua le MNU ae fa'atūina se masini tu'u fa'alaua'itele gaogao.
I isumu na maua le testosterone e aunoa ma ni vailaʻau faʻamaʻi, 10% i le 18% na atiaʻe le kanesa prostate. O le togafitiga o le Testosterone na o ia e leʻi faʻaosoina ai ni tumo faʻapitoa i isi nofoaga, ae faʻatusatusa i isumu faʻatonutonu, na mafua ai le faʻatupulaia tele o le numera o isumu e iai tumo leaga i soʻo se nofoaga. Pe a aafia isumu i testosterone ma carcinogens, o lenei togafitiga e mafua ai le 50% i le 71% o isumu e atiaʻe ai le kanesa prostate. E tusa lava pe maualalo tele le fua o le hormone e faʻateleina ai le maualuga o le testosterone i totonu o le toto, o le afa o isumu o loʻo mafatia pea i tuma prostate. O manu na aafia i vailaʻau faʻamaʻi ae leʻi maua i le testosterone e leʻi atiaʻe le kanesa prostate.
"Talu ai o le atinaʻeina o togafitiga testosterone e fou, ma o le kanesa prostate o se faʻamaʻi faʻasolosolo malie, e leai se faʻamatalaga e iloa ai pe faʻateleina e le testosterone le lamatiaga o le kanesa prostate i tagata," o le tala lea a Boslan. "E ui lava na faia suʻesuʻega a tagata, e atamai le faʻatapulaʻaina o faʻatonuga o le testosterone i tamaloloa e iai faʻamaʻi faʻamaʻi hypogonadism, ma aloese mai alii e faʻaaogaina le testosterone mo faʻamoemoega faʻafomaʻi, e aofia ai le faʻaalia o faʻailoga masani o le matua."
O le suʻesuʻega ua faʻaulutalaina "Testosterone therapy o se faʻaleleia lelei o le tumo mo le prostate rat" ua faʻasalalau i luga ole laiga aʻo leʻi lolomiina.
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Taimi meli: Sep-09-2021