Nkag siab Pentoxifylline: Kev Pom Zoo

Pentoxifylline yog ib hom tshuaj uas muaj nyob rau hauv chav kawm ntawm cov tshuaj hu ua xanthine derivatives. Nws yog feem ntau sau rau kev kho mob ntawm ntau yam kab mob ntawm cov hlab plawv, nrog rau cov kab mob peripheral vascular, intermittent claudication, thiab venous ulcers. Kab lus no muab cov lus qhia dav dav ntawm pentoxifylline, suav nrog nws cov txheej txheem ntawm kev ua, kev siv tshuaj kho mob, cov kev mob tshwm sim, thiab kev ceev faj.

Mechanism ntawm Action

Pentoxifylline siv nws cov kev kho mob feem ntau los ntawm kev txhim kho cov ntshav khiav thiab ncig. Nws ua haujlwm los ntawm inhibiting enzyme phosphodiesterase, uas ua rau nce qib ntawm cyclic adenosine monophosphate (cAMP) hauv hlwb. Kev nce qib cAMP ua rau kom txo qis ntawm vascular du nqaij thiab dilation ntawm cov hlab ntsha, yog li txhim kho cov ntshav ntws mus rau qhov chaw cuam tshuam. Tsis tas li ntawd, pentoxifylline txo cov viscosity ntawm cov ntshav, ua rau nws tsis tshua tsim cov ntshav txhaws thiab txhim kho qhov hloov pauv ntawm cov qe ntshav liab.

Kev siv kho mob

Peripheral Vascular Disease (PVD): Pentoxifylline feem ntau yog siv los kho cov kab mob peripheral vascular, ib qho mob uas tshwm sim los ntawm kev nqaim lossis txhaws ntawm cov hlab ntsha hauv caj npab, ceg, lossis lwm qhov hauv lub cev. Los ntawm kev txhim kho cov ntshav ntws mus rau thaj chaw cuam tshuam, pentoxifylline pab txo cov tsos mob xws li mob, mob plab, thiab loog loog txuam nrog PVD.

Intermittent Claudication: Intermittent claudication yog ib qho tsos mob ntawm peripheral artery disease (PAD) uas yog mob los yog cramping nyob rau hauv ob txhais ceg thaum lub sij hawm lub cev ua si. Pentoxifylline feem ntau tau muab tshuaj los txo cov tsos mob thiab txhim kho kev tawm dag zog rau cov tib neeg uas muaj kev sib cuam tshuam claudication los ntawm kev ua kom cov ntshav ntws mus rau ob txhais ceg thiab txo cov leeg nqaij ischemia.

Venous Ulcers: Pentoxifylline kuj tseem siv tau rau hauv kev tswj cov kab mob venous, uas yog qhib qhov txhab uas tshwm sim ntawm ob txhais ceg lossis ko taw vim qhov tsis zoo ntawm cov hlab ntsha. Los ntawm kev txhim kho cov ntshav khiav thiab cov ntaub so ntswg oxygenation, pentoxifylline pab hauv kev kho qhov txhab thiab txhawb kev kaw cov kab mob venous.

Tej yam tshwm sim

Thaum pentoxifylline yog feem ntau zoo zam, nws yuav ua rau tej yam kev mob tshwm sim rau qee tus neeg. Cov kev mob tshwm sim muaj xws li xeev siab, ntuav, mob plab, kiv taub hau, mob taub hau, thiab dej ntws tawm. Cov kev mob tshwm sim no feem ntau yog mob me thiab ntuav, daws lawv tus kheej thaum lub cev hloov kho rau cov tshuaj. Txawm li cas los xij, tsis tshua muaj tshwm sim, cov kev mob tshwm sim loj dua xws li kev tsis haum tshuaj, lub plawv dhia tsis zoo, thiab los ntshav yuav tshwm sim, yuav tsum tau kho mob tam sim.

Cov kev ceev faj

Cev xeeb tub thiab lactation: Pentoxifylline yuav tsum tau siv nrog ceev faj hauv cov poj niam cev xeeb tub lossis pub niam mis, vim tias nws tsis tau tsim muaj kev nyab xeeb hauv cov neeg no. Cov kws kho mob tuaj yeem ntsuas cov txiaj ntsig muaj txiaj ntsig tiv thaiv kev pheej hmoo ua ntej muab tshuaj pentoxifylline rau cov poj niam cev xeeb tub lossis lactating cov tib neeg.

Kev Sib Tham Tshuaj: Pentoxifylline tuaj yeem cuam tshuam nrog qee yam tshuaj, suav nrog cov tshuaj tiv thaiv coagulants, tshuaj antiplatelet, thiab theophylline. Kev siv pentoxifylline ib txhij nrog cov tshuaj no tuaj yeem ua rau muaj kev pheej hmoo los ntshav lossis lwm yam tsis zoo. Nws yog ib qho tseem ceeb kom qhia rau cov kws kho mob txog txhua yam tshuaj, tshuaj ntxiv, thiab tshuaj ntsuab uas raug coj los ua kom tsis txhob muaj kev cuam tshuam.

Kaw Xav

Hauv cov ntsiab lus, pentoxifylline yog cov tshuaj siv feem ntau rau kev kho mob ntawm cov hlab ntshav xws li kab mob peripheral vascular, intermittent claudication, thiab venous ulcers. Los ntawm kev txhim kho cov ntshav khiav thiab kev ncig, pentoxifylline pab txo cov tsos mob thiab txhawb kev kho mob rau cov tib neeg uas muaj cov mob no. Txawm hais tias feem ntau zam tau zoo, pentoxifylline tuaj yeem ua rau muaj kev phiv rau qee tus neeg thiab yuav tsum tau siv nrog ceev faj hauv qee cov neeg. Yog tias koj muaj lus nug txog pentoxifylline lossis nws siv, thov tsis txhob yig tiv tauj peb. Peb nyob ntawm no los muab cov ntaub ntawv thiab kev txhawb nqa txog cov tshuaj no thiab nws muaj los ntawm peb cov neeg muab kev ntseeg siab.