Kunzwisisa Pentoxifylline: Yakakwana Yekutarisa

Pentoxifylline mushonga uri wekirasi yemishonga inozivikanwa se xanthine derivatives. Inowanzo kurongerwa kurapwa kwakasiyana-siyana kutenderera kweropa, kusanganisira peripheral vascular disease, intermittent claudication, uye venous ulcers. Ichi chinyorwa chinopa tarisiro yakazara yepentoxifylline, kusanganisira maitiro ayo echiito, mashandisirwo ekurapa, zvinogona kuitika, uye kudzivirira.

Nzira Yekuita

Pentoxifylline inoshandisa maitiro ayo ekurapa kunyanya nekuvandudza kuyerera kweropa uye kutenderera. Inoshanda nekudzivisa enzyme phosphodiesterase, iyo inoguma nekuwedzera kwemazinga e cyclic adenosine monophosphate (cAMP) mukati memasero. Yakakwira cAMP mazinga anotungamira mukuzorodza kwevascular smooth tsandanyama uye kuwedzera kwetsinga dzeropa, nekudaro kunatsiridza kuyerera kweropa kunzvimbo dzakakanganisika. Pamusoro pezvo, pentoxifylline inoderedza viscosity yeropa, zvichiita kuti isaite mukana wekuumba magwamba uye kuvandudza kuchinjika kwemasero matsvuku eropa.

Kurapa Kushandiswa

Peripheral Vascular Disease (PVD): Pentoxifylline inowanzoshandiswa kurapwa kwechirwere chevascular peripheral, chirwere chinoratidzwa nekutetepa kana kuvhara kwetsinga dzeropa mumaoko, makumbo, kana dzimwe nhengo dzemuviri. Nekuvandudza kuyerera kweropa kunzvimbo dzakakanganisika, pentoxifylline inobatsira kuderedza zviratidzo zvakadai sekurwadziwa, kurovera, uye chiveve chine chekuita nePVD.

Intermittent Claudication: Intermittent claudication chiratidzo cheperipheral artery disease (PAD) inoratidzwa nekurwadziwa kana kuputika mumakumbo panguva yekurovedza muviri. Pentoxifylline inowanzo kurongedzerwa kudzikisa zviratidzo uye kunatsiridza kushivirira kwekurovedza muviri muvanhu vane kupindirana claudication nekuwedzera kuyerera kweropa kumakumbo uye kuderedza tsandanyama ischemia.

Venous Ulcers: Pentoxifylline inogona zvakare kushandiswa mukutarisira venous maronda, ari maronda akavhurika anokura pamakumbo kana tsoka nekuda kwekutadza kutenderera kwevenous. Nekuwedzera kuyerera kweropa uye tishu oxygenation, pentoxifylline inobatsira mukupora kwemaronda uye inosimudzira kuvharika kwemaronda emutsinga.

Zvingangoitika Zvikonzero

Apo pentoxifylline inowanzotenderwa zvakanaka, inogona kukonzera mamwe maside effects mune vamwe vanhu. Zvinowanzoitika zvinogona kusanganisira kusvotwa, kurutsa, kusagadzikana mudumbu, dzungu, musoro, uye kurutsa. Izvi zvinowanzova zvinyoro uye zvishoma, zvinogadzirisa pachavo sezvo muviri unogadzirisa kumishonga. Zvisinei, muzviitiko zvisingawanzoitiki, migumisiro yakakomba yakadai seyerergic reactions, kurova kwemwoyo kusina nguva, uye kubuda ropa kunogona kuitika, zvinoda kurapwa nokukurumidza.

Zvekungwaririra

Kubata uye Kuyamwisa: Pentoxifylline inofanira kushandiswa nekuchenjerera muvakadzi vane pamuviri kana vanoyamwisa, sezvo kuchengetedzwa kwayo kusati kwasimbiswa muhuwandu uhu. Varapi vehutano vanogona kuyera mabhenefiti angangotarisana nenjodzi vasati varaira pentoxifylline kune vane nhumbu kana vanoyamwisa.

Kudyidzana Kwezvinodhaka: Pentoxifylline inogona kusangana nemimwe mishonga, kusanganisira anticoagulants, antiplatelet drugs, uye theophylline. Kushandisa pentoxifylline pamwe chete nemishonga iyi kunogona kuwedzera njodzi yekubuda ropa kana zvimwe zvinokanganisa. Zvakakosha kuzivisa varapi vehutano nezvese mishonga, ma supplements, uye mishonga yemakwenzi iri kutorwa kudzivirira kusangana kungangoitika.

Kuvhara Pfungwa

Muchidimbu, pentoxifylline mushonga unoshandiswa kunyanya kurapa kusagadzikana kwekutenderera kweropa senge peripheral vascular disease, intermittent claudication, uye venous ulcers. Nekuvandudza kuyerera kweropa uye kutenderera, pentoxifylline inobatsira kuderedza zviratidzo uye kukurudzira kuporeswa kune vanhu vane mamiriro aya. Nepo kazhinji inotenderwa zvakanaka, pentoxifylline inogona kukonzera mhedzisiro mune vamwe vanhu uye inofanirwa kushandiswa nekuchenjerera mune vamwe vanhu. Kana iwe uine chero mibvunzo nezve pentoxifylline kana mashandisiro ayo, ndapota usazeza taura nesu. Isu tiri pano kuti tipe ruzivo nerutsigiro maererano nemushonga uyu uye kuwanikwa kwawo kubva kune vatinovimba navo vatengesi.